Cha Hyunkyung, Song Yoonjae, Bae Yun Jung, Won Tae-Bin, Kim Jeong-Whun, Cho Sung-Woo, Rhee Chae-Seo
Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2020 May;13(2):157-163. doi: 10.21053/ceo.2019.00836. Epub 2019 Nov 2.
This study aimed to evaluate the clinical characteristics of maxillary sinus fungus ball (MFB) to increase the preoperative diagnostic accuracy.
A retrospective review of 247 patients who underwent endoscopic sinus surgery for unilateral maxillary sinusitis from January 2015 to December 2017 at a single institution was performed. Patients with pathologically proven MFB were compared to those with unilateral chronic maxillary sinusitis (CMS). Patient demographics and computed tomography (CT) findings were evaluated. The CT features were categorized as intralesional hyperdensity (calcification), the irregular lobulated protruding lesion (fuzzy appearance), maxillary sinus full haziness without mass effect, maxillary sinus full haziness with mass effect, and others. A regression tree analysis was performed.
In total, 247 patients were analyzed; among them, 179 (72.5%) had MFB and 68 (27.5%) had CMS. MFB showed predominance in older individuals. Among the radiological features, intralesional hyperdensity was most commonly associated with MFB. The presence of a fuzzy appearance or full opacity with mass effect was also associated with MFB. The highest area under the curve was noted with the regression tree analysis based on the model, which included the presence of intralesional hyperdensity, demographic data (age), and presence of fuzzy appearance or maxillary sinus full haziness with mass effect in case of absence of intralesional hyperdensity (0.904).
A simple algorithm to optimize the preoperative diagnosis of MFB was developed. Physicians should be aware of such findings in the management of patients presenting with unilateral CMS.
本研究旨在评估上颌窦真菌球(MFB)的临床特征,以提高术前诊断准确性。
对2015年1月至2017年12月在单一机构接受单侧上颌窦炎内镜鼻窦手术的247例患者进行回顾性研究。将经病理证实为MFB的患者与单侧慢性上颌窦炎(CMS)患者进行比较。评估患者的人口统计学资料和计算机断层扫描(CT)结果。CT特征分为病灶内高密度(钙化)、不规则分叶状突出病变(模糊外观)、上颌窦完全模糊无占位效应、上颌窦完全模糊有占位效应及其他。进行回归树分析。
共分析247例患者;其中,179例(72.5%)患有MFB,68例(27.5%)患有CMS。MFB在老年人中更为常见。在放射学特征中,病灶内高密度最常与MFB相关。模糊外观或有占位效应的完全不透明也与MFB相关。基于该模型的回归树分析得出的曲线下面积最高,该模型包括病灶内高密度的存在、人口统计学数据(年龄),以及在无病灶内高密度情况下模糊外观或上颌窦完全模糊有占位效应的存在(0.904)。
开发了一种优化MFB术前诊断的简单算法。医生在处理单侧CMS患者时应了解这些发现。