Nomura Kazuhiro, Asaka Daiya, Nakayama Tsuguhisa, Okushi Tetsushi, Matsuwaki Yoshinori, Yoshimura Tsuyoshi, Yoshikawa Mamoru, Otori Nobuyoshi, Kobayashi Toshimitsu, Moriyama Hiroshi
Department of Otorhinolaryngology, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan ; Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
Int J Otolaryngol. 2013;2013:731640. doi: 10.1155/2013/731640. Epub 2013 Nov 12.
Sinus fungus ball is defined as noninvasive chronic fungal rhinosinusitis occurring in immunocompetent patients with regional characteristics. The clinical and imaging characteristics of paranasal sinus fungus ball were retrospectively investigated in 104 Japanese patients. All patients underwent endoscopic sinus surgery. Preoperative computed tomography (CT), magnetic resonance (MR) imaging, age, sex, chief complaint, causative fungus, and clinical outcome were analyzed. Patients were aged from 25 to 79 years (mean 58.8 years). Female predominance was noted (58.7%). Most common symptoms were nasal discharge and facial pain. CT showed high density area in 82.0% of the cases (82/100), whereas T2-weighted MR imaging showed low intensity area in 100% of the cases (32/32). Histological examination showed that most causative agents were Aspergillus species (94.2% (98/104)). Culture test was positive for 16.7% (11/66). Recurrence was found in 3.2% (3/94). Older age and female predominance were consistent with previous reports. MR imaging is recommended to confirm the diagnosis.
鼻窦真菌球被定义为发生在免疫功能正常患者中的具有区域特征的非侵袭性慢性真菌性鼻-鼻窦炎。对104例日本患者的鼻窦真菌球的临床和影像学特征进行了回顾性研究。所有患者均接受了鼻内镜鼻窦手术。分析了术前计算机断层扫描(CT)、磁共振(MR)成像、年龄、性别、主要症状、致病真菌及临床结果。患者年龄在25至79岁之间(平均58.8岁)。女性占优势(58.7%)。最常见的症状是流涕和面部疼痛。CT显示82.0%的病例(82/100)有高密度区,而T2加权MR成像显示100%的病例(32/32)有低强度区。组织学检查显示,大多数病原体为曲霉菌属(94.2%(98/104))。培养试验阳性率为16.7%(11/66)。复发率为3.2%(3/94)。年龄较大和女性占优势与既往报道一致。建议采用MR成像来确诊。