Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Br J Ophthalmol. 2020 Aug;104(8):1161-1163. doi: 10.1136/bjophthalmol-2019-314980. Epub 2019 Nov 1.
To investigate spontaneous resolution of congenital nasolacrimal duct obstruction (CNLDO) beyond 12 months of age in Japanese infants.
Retrospective, observational case series. We retrospectively reviewed the clinical records of patients diagnosed with CNLDO beyond 12 months of age at Kyoto Prefectural University Hospital, Kyoto, Japan. This study involved 155 cases of CNLDO in 133 Japanese infants diagnosed with CNLDO. All patients chose intervention with either dacryoendoscopic guided probing and stenting or conservative management. The proportion and age of patients who had spontaneous CLNDO resolution were analysed.
The patients were divided into two groups: (1) 62 patients with 70 obstructed nasolacrimal ducts (45%) in whom spontaneous resolution occurred and (2) 71 patients with 85 obstructed nasolacrimal ducts (55%) who underwent dacryoendoscopic guided probing and stenting. The mean age of spontaneous resolution was 17.8±5.3 months (range: 12.0-35.4 months). Dacryoendoscopic guided probing and stenting were successful in 83/85 (97.6%) of cases.
Spontaneous resolution of CNLDO can occur in 45% of infants over the age of 12 months. Dacryoendoscopic guided stenting also has high success rates in this patient group, and both treatment options can be proposed to caregivers.
研究日本婴儿超过 12 个月的先天性鼻泪管阻塞（CNLDO）的自发缓解情况。
回顾性、观察性病例系列研究。我们回顾性地审查了在日本京都府立大学医院被诊断为超过 12 个月的 CNLDO 的患者的临床记录。本研究涉及 133 例日本婴儿的 155 例 CNLDO 病例。所有患者均选择行泪道内镜引导下探通置管术或保守治疗。分析自发缓解 CNLDO 的患者比例和年龄。
患者分为两组：（1）62 例 70 条鼻泪管阻塞（45%）患者出现自发缓解，（2）71 例 85 条鼻泪管阻塞患者行泪道内镜引导下探通置管术。自发缓解的平均年龄为 17.8±5.3 个月（范围：12.0-35.4 个月）。85 例中的 83 例（97.6%）行泪道内镜引导下探通置管术成功。
超过 12 个月的婴儿中，45%的 CNLDO 可自发缓解。泪道内镜引导下置管术在该患者群体中也有很高的成功率，可向患儿家属提出两种治疗选择。
