Garfinkel L, Stellman S D
Department of Epidemiology and Statistics, American Cancer Society, New York, NY 10001.
Cancer. 1988 Oct 15;62(8 Suppl):1844-50. doi: 10.1002/1097-0142(19881015)62:1+<1844::aid-cncr2820621328>3.0.co;2-o.
Mortality in relation to relative weight and exercise was analyzed from data collected in the first 2 years of the American Cancer Society's Cancer Prevention Study II. It included data on 868,620 persons who had no history of cancer, heart disease, or stroke and who were not sick at the start of the study. Standardized mortality ratios (SMR) were 187 for men who were 20% or more underweight and 187 for men who were 40% or more overweight. Comparable SMR in women were 186 and 178. Current smokers had considerably higher SMR than nonsmokers for all causes of death and cancer deaths at each relative weight category. Degree of exercise reported by subjects was inversely related to mortality, independent of smoking habits. Subjects who exercised heavily and died of cancer of the lung, colon-rectum, and pancreas had 20% to 37% higher SMR than men and women who reported moderate exercise.
根据美国癌症协会癌症预防研究II前两年收集的数据，分析了死亡率与相对体重和运动的关系。该研究纳入了868,620名无癌症、心脏病或中风病史且在研究开始时未患病的人群。体重低于标准体重20%或更多的男性标准化死亡率（SMR）为187，超重40%或更多的男性标准化死亡率也为187。女性的相应标准化死亡率分别为186和178。在每个相对体重类别中，当前吸烟者因所有死因和癌症死亡的标准化死亡率均显著高于非吸烟者。受试者报告的运动程度与死亡率呈负相关，且与吸烟习惯无关。大量运动且死于肺癌、结肠直肠癌和胰腺癌的受试者，其标准化死亡率比报告适度运动的男性和女性高20%至37%。
