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非高加索族裔与高加索族裔女性妊娠糖尿病的特征比较。

Characteristics of Women With Gestational Diabetes From Non-Caucasian Compared With Caucasian Ethnic Groups.

机构信息

Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.

Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada.

出版信息

Can J Diabetes. 2019 Dec;43(8):600-605. doi: 10.1016/j.jcjd.2019.09.005. Epub 2019 Sep 27.

Abstract

OBJECTIVES

Short- and long-term outcomes in women after gestational diabetes mellitus (GDM) vary by ethnicity. Understanding differences in baseline diabetes risk factors is important for informing choice of risk-reducing interventions. We aimed to compare maternal and pregnancy-related characteristics in Caucasian and non-Caucasian women with GDM.

METHODS

Using a large multicentre Canadian cohort of women diagnosed with GDM and recruited between 2009 and 2013, we compared demographic, clinical and behavioural characteristics in women with GDM across 7 ethnic groups. Data were obtained from chart reviews and surveys, and logistic and linear regression models were used to compare binary and continuous variables, respectively, between Caucasian and non-Caucasian ethnic groups.

RESULTS

Of the 1,332 women with GDM, 911 were eligible for inclusion. Of these, 41.4% were white Caucasian, 17.1% were South Asian, 18.4% were East Asian, 5.8% were black, 8.8% were Filipina, 5.2% were Middle Eastern and 3.3% were Hispanic. Non-Caucasian women were diagnosed with GDM at a younger age and were more likely to have a family history of diabetes compared with Caucasian women. With the exception of East Asians, non-Caucasian women were more likely to be overweight using ethnicity-specific body mass index cutoffs and have higher oral glucose tolerance test values than Caucasian women. Prepregnancy smoking and alcohol consumption prevalence were highest in Caucasian women.

CONCLUSIONS

Several important ethnicity-specific differences in clinical and behavioural characteristics of women with GDM were identified. These differences need to be considered when offering interventions for reducing risk of adverse perinatal outcomes and subsequent type 2 diabetes.

摘要

目的

妊娠糖尿病(GDM)后女性的短期和长期结局因种族而异。了解基线糖尿病风险因素的差异对于告知选择降低风险的干预措施很重要。我们旨在比较 GDM 白种人和非白种女性的孕产妇和妊娠相关特征。

方法

使用加拿大一项大型多中心队列研究,该研究纳入了 2009 年至 2013 年间诊断为 GDM 的女性,我们比较了 7 个种族群体中 GDM 女性的人口统计学、临床和行为特征。数据来自病历回顾和调查,使用逻辑和线性回归模型分别比较白种人和非白种人种族群体之间的二分类和连续变量。

结果

在 1332 名患有 GDM 的女性中,有 911 名符合纳入标准。其中,41.4%是白人,17.1%是南亚人,18.4%是东亚人,5.8%是黑人,8.8%是菲律宾人,5.2%是中东人,3.3%是西班牙裔。与白种人女性相比,非白种人女性诊断 GDM 的年龄更小,且更有可能有糖尿病家族史。除东亚人外,非白种人女性的体重指数(BMI)更有可能超过种族特异性 BMI 切点,且口服葡萄糖耐量试验(OGTT)值高于白种人女性。白种人女性中,孕前吸烟和饮酒的比例最高。

结论

确定了 GDM 女性的临床和行为特征中几个重要的种族特异性差异。在提供降低不良围产期结局和随后 2 型糖尿病风险的干预措施时,需要考虑这些差异。

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