Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Phytother Res. 2020 Feb;34(2):418-427. doi: 10.1002/ptr.6534. Epub 2019 Nov 3.
The World Health Organization has recommended herbal medicine for treatment and control of recurrent cystitis. This study was conducted to determine effect of eshnan on the prevention of recurrent cystitis. The present triple-blind clinical trial was conducted on 126 women (63 women per group) with recurrent cystitis. The participants were assigned to the intervention and control groups. Three 500-mg eshnan or placebo tablets were taken orally with a glass full of water by the participants half an hour after each meal for 2 months. The study subjects were clinically and paraclinically evaluated by the end of the second, fourth, and sixth months after the intervention and every time they showed clinical symptoms of cystitis. The present findings showed that the incidence rate of cystitis and symptoms of cystitis was significantly lower in the eshnan group compared with the placebo group 2, 4, and 6 months after the intervention (p < .05). The incidence of recurrent was also significantly lower in the intervention group compared with the control group (p < .001). No side effects were observed in the intervention and control groups. The consumption of eshnan can improve the symptoms of cystitis and prevent the incidence of recurrent cystitis in women of reproductive age.
世界卫生组织推荐草药治疗和控制复发性膀胱炎。本研究旨在确定 eshanan 对预防复发性膀胱炎的影响。这项三盲临床试验共纳入 126 名复发性膀胱炎女性患者（每组 63 名）。参与者被分配到干预组和对照组。两组参与者分别在餐后半小时内口服 3 片 500 毫克的 eshanan 或安慰剂，每天 3 次，持续 2 个月。在干预后第 2、4 和 6 个月以及每次出现膀胱炎临床症状时，对研究对象进行临床和辅助临床评估。研究结果表明，与安慰剂组相比，干预组在干预后 2、4 和 6 个月时膀胱炎的发生率和膀胱炎症状明显更低（p <.05）。与对照组相比，干预组的复发性膀胱炎发生率也明显更低（p <.001）。干预组和对照组均未观察到不良反应。食用 eshanan 可改善膀胱炎症状，预防育龄妇女复发性膀胱炎的发生。
