Slesarevskaya M N, Kuzmin I V, Al-Shukri S Kh
Department of Urology, First Pavlov State Medical University of St. Petersburg, St. Petersburg, Russia.
Urologiia. 2018 Mar(1):30-34.
Recurrent lower urinary tract infections (UTI) in women are one of the most challenging problems of modern urology, which is associated both with their high incidence and increasing resistance of uropathogens to antibacterial drugs. Due to this fact, the phytotherapy of infectious and inflammatory diseases of the urinary tract has received increased attention.
To investigate the effectiveness of Phytolysin nefroCAPS in the complex management of women with chronic recurrent cystitis.
50 women with chronic recurrent cystitis underwent a complex examination. They were divided into two groups depending on the treatment they received. Patients of the 1st group (n=27) received a combination therapy: fosfomycin (monural) 3 g (single dose) and Phytolysin nefroCAPS one capsule three times daily for three months. Patients of the 2nd group (n=23) were administered a single 3-g dose of fosfomycin (monural).
Follow-up examinations were performed 1, 3 and six months after initiation of the treatment. In patients of the 1st group, clinical manifestations of the disease disappeared earlier, and they had fewer recurrences than the patients of the 2nd group. Also, bacteriological study of urine showed a more persistent antimicrobial effect among patients of the 1st group.
In patients with chronic recurrent cystitis, plant-based preparation Phytolysin nefroCAPS administered concurrently with an antibacterial drug is more effective than antibiotic monotherapy.
女性复发性下尿路感染（UTI）是现代泌尿外科最具挑战性的问题之一，这与其高发病率以及尿路病原体对抗菌药物耐药性增加有关。鉴于此，尿路传染性和炎性疾病的植物疗法受到了更多关注。
研究Phytolysin nefroCAPS在慢性复发性膀胱炎女性综合治疗中的有效性。
50例慢性复发性膀胱炎女性接受了综合检查。根据所接受的治疗将她们分为两组。第一组（n = 27）患者接受联合治疗：磷霉素（莫诺苷）3 g（单次剂量）和Phytolysin nefroCAPS，每日三次，每次一粒，共三个月。第二组（n = 23）患者给予单次3 g剂量的磷霉素（莫诺苷）。
在治疗开始后1、3和6个月进行随访检查。第一组患者疾病的临床表现消失得更早，复发次数比第二组患者少。此外，尿液细菌学研究显示第一组患者的抗菌作用更持久。
在慢性复发性膀胱炎患者中，与抗菌药物同时使用的植物制剂Phytolysin nefroCAPS比单一抗生素治疗更有效。
