Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK.
Rheumatology (Oxford). 2019 Nov 1;58(Suppl 5):v22-v28. doi: 10.1093/rheumatology/kez310.
Non-pharmacological interventions may be beneficial in the management of rheumatoid arthritis related fatigue. A narrative review was undertaken, with a focus upon research published in the past 6 years. Seven studies were identified, four focusing upon physical activity, two on psychosocial interventions and one that investigated aromatherapy and reflexology. Findings supported previous evidence that physical activity and psychosocial interventions have potential to produce small to moderate reductions in fatigue related to rheumatoid arthritis. Reflexology and aromatherapy interventions also appeared promising. Limitations to the evidence included lack of consistency in fatigue measurement, and minimal data on long-term outcomes and cost effectiveness. The wide range of physical activity interventions prevent specific recommendations. For psychosocial interventions the strongest evidence is for group-based cognitive behavioural approaches. There was lack of consideration given to fatigue mechanisms and intervention design. Due to the complexity of fatigue, future research exploring personalized approaches is warranted.
非药物干预措施可能有益于类风湿关节炎相关疲劳的管理。进行了叙述性评论，重点是过去 6 年发表的研究。确定了 7 项研究，其中 4 项侧重于体育活动，2 项侧重于心理社会干预，1 项研究芳香疗法和反射疗法。研究结果支持了先前的证据，即体育活动和心理社会干预有可能适度减轻与类风湿关节炎相关的疲劳。反射疗法和芳香疗法干预似乎也有希望。证据的局限性包括疲劳测量缺乏一致性，以及关于长期结果和成本效益的资料很少。各种体育活动干预措施使得无法提出具体建议。对于心理社会干预，最有力的证据是基于群体的认知行为方法。对于疲劳机制和干预设计没有给予充分考虑。由于疲劳的复杂性，有必要进行未来探索个性化方法的研究。
