Miao Xutao, Xin Zhonghai
Department of Otolaryngology, Beijing United Family Hospital, Beijing, China.
Department of Otolaryngology, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Undersea Hyperb Med. 2019;46(5):659-663.
Treatment of idiopathic sensorineural hearing loss (ISSNHL) is problematic due to the unclear etiology of the illness. Corticosteroid is recommended by some papers, and hyperbaric oxygen (HBO2) by others. Recently HBO2 has been shown to be an important therapy for ISSNHL, with an increasing number of studies demonstrating its beneficial results. Recovery from ISSNHL depends on the interval period between onset and treatment, hearing loss severity and audiogram type used to determine damage. Treatment of ISSNHL requires a detailed analysis. In this retrospective study we reviewed data from 56 patients with moderate ISSNHL. These patients were divided into three groups based on different treatments: corticosteroid group; corticosteroid + HBO2 (combination)group; and HBO2-only group. Additionally, all patients received intravenous vasodilator treatment. Hearing levels before and after treatment were compared. All three groups had a similar recovery rate, with an effective rate of more than 50%, and a hearing gain average of 17.38 decibels (dB). HBO2 treatment got a higher recovery rate. The combination therapy, which included corticosteroid and HBO2, did not elevate the recovery rate.
由于特发性感音神经性听力损失（ISSNHL）的病因不明，其治疗存在问题。一些论文推荐使用皮质类固醇，另一些则推荐高压氧（HBO2）。最近，HBO2已被证明是ISSNHL的一种重要治疗方法，越来越多的研究证明了其有益效果。ISSNHL的恢复取决于发病与治疗之间的间隔期、听力损失的严重程度以及用于确定损伤的听力图类型。ISSNHL的治疗需要详细分析。在这项回顾性研究中，我们回顾了56例中度ISSNHL患者的数据。这些患者根据不同的治疗方法分为三组：皮质类固醇组；皮质类固醇+HBO2（联合）组；以及仅HBO2组。此外，所有患者均接受静脉血管扩张剂治疗。比较治疗前后的听力水平。所有三组的恢复率相似，有效率超过50%，听力平均增益为17.38分贝（dB）。HBO2治疗的恢复率更高。包括皮质类固醇和HBO2的联合治疗并未提高恢复率。
