Neyisci Cagri, Erdem Yusuf
Orthopaedics and Traumatology, Gulhane Training and Research Hospital, Ankara, TUR.
Orthopaedics, Gulhane Training and Research Hospital, Ankara, TUR.
Cureus. 2019 Aug 29;11(8):e5526. doi: 10.7759/cureus.5526.
Introduction Osteoid osteoma (OO) is a painful, benign, bone-forming tumor characterized by a small central nidus surrounded by sclerotic tissue. The aim of the present study was to evaluate the clinical outcome after computed tomography (CT)-guided radiofrequency ablation (RFA) in patients with OO performed from January 2012 to June 2018 and to confirm the safety and efficacy of CT-guided RFA. Methods Between January 2012 and June 2018, a total of 63 patients were treated with CT-guided RFA. Pre- and post-treatment pain, further treatment after the RFA procedure, observed complications, and satisfaction with the treatment were recorded for an assessment of clinical effects in all patients. The patients were evaluated with the visual analog scale (VAS) pre-procedure and at three months post-procedure. Results Of the patients, 39 were males and 24 were females with a mean age of 21 ± 9.7 (range, 9 to 41) years. The mean follow-up was 16 ± 2.1 (range, 12 to 19) months. The mean duration of the procedure was 34 ± 11.4 (range, 22 to 47) min. All of the patients were diagnosed with OO pathologically. A statistically significant difference was found between the pre-procedural and post-procedural VAS scores (p<0.001). Complications were observed in six patients including one peroneal nerve lesion, three minor skin burns, and two minor skin infections. Conclusion This study shows that CT-guided RFA is a safe and effective treatment for OO. It is thought that RFA could be the primary treatment choice for most OO with typical symptoms and radiological findings.
引言
骨样骨瘤(OO)是一种引起疼痛的良性成骨性肿瘤,其特征为一个小的中央瘤巢被硬化组织包绕。本研究的目的是评估2012年1月至2018年6月期间接受计算机断层扫描(CT)引导下射频消融(RFA)治疗的骨样骨瘤患者的临床结局,并确认CT引导下RFA的安全性和有效性。
方法
2012年1月至2018年6月期间,共有63例患者接受了CT引导下RFA治疗。记录所有患者治疗前和治疗后的疼痛情况、RFA术后的进一步治疗、观察到的并发症以及对治疗的满意度,以评估临床效果。在术前和术后三个月采用视觉模拟评分法(VAS)对患者进行评估。
结果
患者中,男性39例,女性24例,平均年龄21±9.7岁(范围9至41岁)。平均随访时间为16±2.1个月(范围12至19个月)。手术平均持续时间为34±11.4分钟(范围22至47分钟)。所有患者经病理诊断为骨样骨瘤。术前和术后VAS评分之间存在统计学显著差异(p<0.001)。6例患者出现并发症,包括1例腓总神经损伤、3例轻度皮肤烧伤和2例轻度皮肤感染。
结论
本研究表明,CT引导下RFA是治疗骨样骨瘤的一种安全有效的方法。对于大多数具有典型症状和影像学表现的骨样骨瘤,RFA被认为可能是主要的治疗选择。