Department of Diagnostic and Interventional Radiology, University of Heidelberg, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany.
Eur J Radiol. 2012 Nov;81(11):3426-34. doi: 10.1016/j.ejrad.2012.04.037. Epub 2012 Jul 6.
The purpose of this study was to retrospectively evaluate long-term success of CT-guided radiofrequency ablation (RFA) in patients with osteoid osteoma (OO) and osteoblastoma (OB) including tumors in critical locations. Eighty-one CT-guided RFA procedures were performed in 77 patients with OO (65 patients) and OB (12) including 6 spinal and 15 intra/periarticular tumors. Procedural techniques included multiple needle positions, three-dimensional access planning, as well as, thermal protection techniques. Long-term success was assessed using a questionnaire including, among others, several VAS (visual analogue scale) scores. All patients completed 3-6 months follow-up, overall response to the questionnaire was 64/77 (83.1%). Primary success rate was 74/77 (96.1%) of all patients. Retreatment with RFA in 3 patients resulted in a secondary success rate of 77/77 (100%). Long-term follow-up (mean, 38.5 months; range, 3-92) revealed a highly significant (p<0.001) reduction of all assessed limitation scores reaching normal or almost normal values. One major complication, a cannula break leading to a secondary short hospital stay, occurred. In conclusion, RFA is a safe and effective long-lasting treatment of OO and OB. Advanced procedural techniques aid treating tumors in critical locations and in the coverage of larger tumors. Besides night pain, RFA also greatly improves other factors negatively affecting the quality of life.
本研究旨在回顾性评估 CT 引导下射频消融 (RFA) 治疗骨样骨瘤 (OO) 和骨母细胞瘤 (OB) 患者的长期疗效,包括位于关键部位的肿瘤。77 例患者中的 65 例 OO 和 12 例 OB 患者共进行了 81 次 CT 引导下 RFA 手术,包括 6 例脊柱和 15 例关节内/周围肿瘤。手术技术包括多针位、三维入路规划以及热保护技术。通过问卷调查评估长期疗效,包括多个视觉模拟量表 (VAS) 评分。所有患者均完成 3-6 个月随访,77/77 (83.1%) 例患者对问卷做出回应。所有患者的初次成功率为 74/77 (96.1%)。3 例患者行 RFA 再次治疗,二次成功率为 77/77 (100%)。长期随访 (平均 38.5 个月,范围 3-92 个月) 显示,所有评估受限评分均显著降低 (p<0.001),达到正常或接近正常水平。仅发生 1 例主要并发症,即导丝断裂导致再次短期住院,无其他严重并发症。结论:RFA 是治疗 OO 和 OB 的一种安全、有效的长期方法。先进的手术技术有助于治疗关键部位和较大肿瘤的肿瘤。除夜间疼痛外,RFA 还极大地改善了其他影响生活质量的因素。