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术后第一周的疼痛可预测近节指骨骨折固定术后十二周的疼痛及手部功能使用情况。

Pain in the Post-Operative Week Predicts Pain and Hand Use Twelve Weeks after Proximal Phalangeal Fracture Fixation.

作者信息

Miller Lauren, Ada Louise, Crosbie Jack, Wajon Anne

机构信息

Hand Therapy Unit, Sydney Hospital, Sydney, Australia.

The University of Sydney, Faculty of Health Sciences, Sydney, Australia.

出版信息

J Hand Surg Asian Pac Vol. 2019 Dec;24(4):462-468. doi: 10.1142/S2424835519500607.

Abstract

The purpose of this study was to determine whether baseline characteristics predict outcomes twelve weeks after open reduction and internal fixation of proximal phalangeal fracture. A cohort of patients (n = 48, mean 35 years; SD 11) commencing outpatient rehabilitation within one week of surgery were reviewed. Outcomes of interest were active PIP extension; active total range of motion; pain at rest; comprehensive pain; strength; and hand use (reported difficulty performing specific activities such as turning a door handle, as well as usual activities including housework and recreation) at twelve weeks. Possible predictors included which finger is injured, whether the fracture is intra or extra-articular, whether the dominant or non-dominant hand is injured and/or how much pain is experienced in the first post-operative week. Multiple linear regression was performed to produce a model of the prediction for each outcome of interest at Week 1 (baseline). Results from multivariate linear regression analyses suggest that pain at rest at baseline was significantly predictive of pain at rest (OR = 1.25, 95% CI = 1.06-1.47), = 0.01), comprehensive pain (OR = 3.18, 95% CI = 1.47-6.84, = 0.01), and hand use (OR = 2.38, 95% CI = 1.18-4.80, = 0.02) twelve weeks after open reduction and internal fixation of proximal phalangeal fracture. The turning point on the receiver-operator characteristic curve of false versus true risk (AUC = 0.94, = 0.04) indicated that at least a score of 4.5 on the 10 cm visual analogue scale for baseline resting pain was needed for significant likelihood of reduced hand use. Which finger was injured, location of fracture and side of injury were not predictive of any outcomes. Moderate to high levels of resting pain in the week following surgery for proximal phalangeal fracture is predictive of pain and hand use at twelve weeks. Moderate to high levels of resting pain should be recognised as unusual, and could be targeted in rehabilitation. Further prospective studies are needed to determine whether early identification and targeted intervention to reduce pain improves outcomes at 12 weeks.

摘要

本研究的目的是确定在近节指骨骨折切开复位内固定术后12周,基线特征是否能够预测预后情况。对一组在术后一周内开始门诊康复治疗的患者(n = 48,平均年龄35岁;标准差11)进行了回顾性研究。感兴趣的预后指标包括:主动的近端指间关节(PIP)伸展;主动的总活动范围;静息痛;综合疼痛;力量;以及12周时的手部功能使用情况(报告在进行诸如转动门把手等特定活动以及包括家务和娱乐在内的日常活动时存在困难)。可能的预测因素包括受伤手指、骨折是关节内还是关节外、受伤的是优势手还是非优势手以及术后第一周经历的疼痛程度。进行多元线性回归以建立第1周(基线)时每个感兴趣的预后指标的预测模型。多变量线性回归分析结果表明,基线时的静息痛对近节指骨骨折切开复位内固定术后12周的静息痛(比值比[OR] = 1.25,95%置信区间[CI] = 1.06 - 1.47,P = 0.01)、综合疼痛(OR = 3.18,95% CI = 1.47 - 6.84,P = 0.01)和手部功能使用情况(OR = 2.38,95% CI = 1.18 - 4.80,P = 0.02)具有显著预测作用。真风险与假风险的受试者工作特征曲线的转折点(曲线下面积[AUC] = 0.94,P = 0.04)表明,对于手部功能使用情况降低的显著可能性,基线静息痛在10厘米视觉模拟量表上至少需要达到4.5分。受伤手指、骨折位置和受伤侧别对任何预后指标均无预测作用。近节指骨骨折术后第一周的中度至高度静息痛可预测12周时的疼痛和手部功能使用情况。中度至高度静息痛应被视为异常情况,并可作为康复治疗的目标。需要进一步的前瞻性研究来确定早期识别和针对性干预以减轻疼痛是否能改善12周时的预后情况。

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