Hematology/Oncology Section, Primary Care Service Line, Minneapolis VA Health Care System, Minneapolis, Minnesota; Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Research Service, Minneapolis VA Health Care System, Minneapolis, Minnesota.
Semin Oncol. 2019 Aug-Oct;46(4-5):321-326. doi: 10.1053/j.seminoncol.2019.10.001. Epub 2019 Oct 24.
Lung cancer is one of the most common and difficult to treat cancers. Veterans are disproportionately affected by lung cancer, as approximately 20% of all cancers diagnosed within the Veteran Affairs health system are lung cancers. Many Veterans have extensive comorbidities, and thus they are often excluded from clinical trials based on this and other eligibility criteria. Thus, while clinical trials are the gold standard to guide treatment decisions, many Veterans' clinical situations will not align with clinical trial criteria. The Department of Veterans Affairs has established a Central Cancer Registry to aid in evaluation of cancer outcomes and other studies, and data in the registry date back to 1995. This has provided a rich source of data for outcome-based and other research. Here, we highlight studies that utilized the Veterans Affairs Central Cancer Registry to analyze lung cancer outcomes in Veterans treated within the Veterans Affairs health system.
肺癌是最常见和最难治疗的癌症之一。退伍军人受肺癌的影响不成比例，因为退伍军人事务部医疗系统中诊断出的所有癌症中，约有 20%是肺癌。许多退伍军人有多种合并症，因此他们经常因这些合并症和其他资格标准而被排除在临床试验之外。因此，虽然临床试验是指导治疗决策的黄金标准，但许多退伍军人的临床情况与临床试验标准不符。退伍军人事务部设立了中央癌症登记处，以帮助评估癌症结果和其他研究，该登记处的数据可追溯到 1995 年。这为基于结果的研究和其他研究提供了丰富的数据来源。在这里，我们重点介绍了利用退伍军人事务部中央癌症登记处分析退伍军人事务部医疗系统中治疗的退伍军人肺癌结果的研究。
