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手术治疗无症状和有症状患者的卒中风险降低:带补片移植血管成形术的颈动脉内膜切除术的有效性。

Stroke risk reduction in asymptomatic and symptomatic patients treated surgically: the effectiveness of carotid endarterectomy with patch graft angioplasty.

作者信息

Deriu G P, Ballotta E, Facco E, Franceschi L, Alvino S, Saia A, Calabrò A, Grego F, Bonavina L

机构信息

Department of Vascular Surgery, University of Padua, School of Medicine, Italy.

出版信息

Eur J Vasc Surg. 1988 Apr;2(2):87-91. doi: 10.1016/s0950-821x(88)80054-9.

DOI:10.1016/s0950-821x(88)80054-9
PMID:3169277
Abstract

From March 1980 to March 1987, 217 consecutive patients underwent 252 carotid revascularisations with routine use of continuous EEG monitoring and selective use of an intraluminal shunt for symptomatic (70%) or asymptomatic (30%) internal carotid artery (ICA) atherosclerotic stenosis. All carotid endarterectomies were routinely performed with a patch graft angioplasty. None of the patients suffered permanent or transient neurological deficits in the immediate postoperative period and none of them died. There was an 0.8% stroke rate and 0.4% mortality rate in the early postoperative course. Neurological assessment, Doppler and Echo doppler sonography of both the operated and the contralateral ICA was performed every 6 months. One-hundred and twenty-one patients (142 carotid revascularisations) operated on up to December 31st 1985 were reassessed in July 1986. The mean follow-up time was 35 months (range: 6 months to 6 years). New neurological symptoms were present in 7.4% of the patients; 2.5% of patients developed a stroke and 8.9% showed progression of stenosis in the contralateral ICA. One patient had a common carotid artery stenosis 2 years after surgery. Re-stenosis of the ICA was found in two patients who underwent re-operation without difficulty. The late mortality was 21.4% (11.9% of the overall series). In only two patients (7.6%) was stroke the cause of death.

摘要

1980年3月至1987年3月,217例连续患者接受了252次颈动脉血运重建术,术中常规使用连续脑电图监测,并根据症状性(70%)或无症状性(30%)颈内动脉(ICA)粥样硬化狭窄情况选择性使用腔内分流器。所有颈动脉内膜切除术均常规进行补片移植血管成形术。术后即刻无患者出现永久性或短暂性神经功能缺损,也无患者死亡。术后早期卒中发生率为0.8%,死亡率为0.4%。每6个月对手术侧和对侧ICA进行神经功能评估、多普勒和超声多普勒检查。对截至1985年12月31日接受手术的121例患者(142次颈动脉血运重建术)于1986年7月进行了重新评估。平均随访时间为35个月(范围:6个月至6年)。7.4%的患者出现新的神经症状;2.5%的患者发生卒中,8.9%的患者对侧ICA狭窄进展。1例患者术后2年出现颈总动脉狭窄。2例接受再次手术的患者顺利发现ICA再狭窄。晚期死亡率为21.4%(占整个系列的11.9%)。仅2例患者(7.6%)死于卒中。

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