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十年颈动脉重建手术的反思

Reflections from a decade of carotid reconstructive surgery.

作者信息

Edwards W H, Jenkins J M, Edwards W H, Mulherin J L

机构信息

Department of Surgery, St. Thomas Hospital, Nashville, Tenn.

出版信息

South Med J. 1988 Apr;81(4):425-9, 451. doi: 10.1097/00007611-198804000-00003.

Abstract

Carotid artery reconstructive surgery for atherosclerotic lesions of the extracranial cerebral circulation has become the most common operation in peripheral vascular surgery. A better understanding of the indications for operative intervention, enhanced monitoring during surgery, and more precise management of intraoperative anesthesia have all helped decrease the risks associated with internal carotid endarterectomy. To evaluate the safety and efficacy of extracranial carotid reconstructive surgery, we reviewed 2,857 operations done on 2,087 patients from 1976 to 1985. Operation was recommended because of hemispheric symptoms in 58%, and because of asymptomatic, significant stenosis in 14%. Postoperative hemiparesis occurred in 24 patients and was associated with thrombosis at the operative site in 18 patients. Antiplatelet drugs used during the last three years were found to be effective in preventing thrombosis at the operative site. Operative mortality during the study period was 1.5%. Follow-up has ranged from one month to 104 months, with 84% of the patients alive and 79% symptom free.

摘要

针对颅外脑循环动脉粥样硬化病变的颈动脉重建手术已成为周围血管外科中最常见的手术。对手术干预指征的更好理解、手术期间加强监测以及术中麻醉更精确的管理,都有助于降低与颈动脉内膜切除术相关的风险。为评估颅外颈动脉重建手术的安全性和有效性,我们回顾了1976年至1985年对2087例患者进行的2857例手术。因半球症状而建议手术的占58%,因无症状的严重狭窄而建议手术的占14%。术后有24例患者出现偏瘫,其中18例与手术部位血栓形成有关。发现过去三年使用的抗血小板药物在预防手术部位血栓形成方面有效。研究期间的手术死亡率为1.5%。随访时间从1个月到104个月不等,84%的患者存活,79%的患者无症状。

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