Frager D H, Wolf E L, Competiello L S, Frager J D, Klein R S, Beneventano T C
Department of Radiology, Montefiore Medical Center--Albert Einstein College of Medicine, Bronx, New York 10467.
Gastrointest Radiol. 1988 Oct;13(4):358-60. doi: 10.1007/BF01889099.
Two patients with Acquired Immunodeficiency Syndrome (AIDS) and infectious esophagitis developed squamous cell carcinoma of the esophagus. The clinical, radiographic, and endoscopic presentations in both cases were atypical. One patient developed a focal flat lesion that imitated segmental esophagitis, and the other patient developed a superficially spreading carcinoma that mimicked diffuse esophagitis. In the setting of AIDS, a changing radiographic or endoscopic mucosal pattern requires biopsy to exclude the possibility of a superimposed squamous cell carcinoma.