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腹腔镜前列腺癌根治术及挽救性放疗后切口部位及腹膜转移

Port site and peritoneal metastasis following laparoscopic radical prostatectomy and salvage radiotherapy for prostate adenocarcinoma.

作者信息

Caño-Velasco Jorge, Herranz-Amo F, Polanco Pujol Lucía, Barbas-Bernardos G, Morelejo-Gárate M, Subirá-Ríos D, Hernández-Fernández C

机构信息

Servicio de Urología. Hospital General Universitario Gregorio Marañón. Madrid. España.

出版信息

Arch Esp Urol. 2019 Nov;72(9):974-977.

PMID:31697261
Abstract

OBJECTIVE

Metastatic involvement in the port site used to perform laparoscopic radical prostatectomy (LRP) is very infrequent.

METHODS

We report the case of a patient with port site and peritoneal metastasis after laparoscopic radical prostatectomy and salvage radiotherapy.

RESULTS

60-year-old male with a history of LRP due to Gleason score 7 (3+4) prostate adenocarcinoma with posterior salvage radiotherapy after biochemical recurrence. Appearance of metastatic lesion at one of the laparoscopic port site followed by third left rib and peritoneal metastasis, treated with local excision and subsequent hormonotherapy and chemotherapy (HT+QT).

CONCLUSIONS

Metastatic extension of prostate adenocarcinoma at a port site after performing laparoscopic radical prostatectomy is a highly exceptional situation. The elevation of PSA levels and image tests (PET-CT) help in the diagnosis. Histopathological confirmation must be performed using Fine Needle Aspiration(FNA). Surgical excision is the treatment of choice. Adjuvant therapy (HT+QT) can help complete the treatment scheme.

摘要

目的

用于进行腹腔镜根治性前列腺切除术(LRP)的端口部位发生转移极为罕见。

方法

我们报告了一例腹腔镜根治性前列腺切除术后出现端口部位及腹膜转移并接受挽救性放疗的患者病例。

结果

一名60岁男性,因 Gleason评分7(3+4)的前列腺腺癌接受了LRP,生化复发后接受了挽救性放疗。在腹腔镜端口部位之一出现转移性病变,随后出现左侧第三肋骨及腹膜转移,接受了局部切除,随后进行了激素治疗和化疗(HT+QT)。

结论

腹腔镜根治性前列腺切除术后前列腺腺癌在端口部位发生转移是一种极为罕见的情况。前列腺特异性抗原(PSA)水平升高及影像检查(PET-CT)有助于诊断。必须通过细针穿刺抽吸(FNA)进行组织病理学确认。手术切除是首选治疗方法。辅助治疗(HT+QT)有助于完善治疗方案。

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