From the Departments of Nuclear Medicine.
Radiation Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Clin Nucl Med. 2023 Apr 1;48(4):e186-e187. doi: 10.1097/RLU.0000000000004544. Epub 2023 Jan 12.
Port-site metastasis is an extremely rare complication following minimally invasive oncologic surgery for prostate cancer. We present the case of a 74-year-old man who underwent robot-assisted laparoscopic radical prostatectomy followed by salvage radiotherapy. Despite treatment, he developed biochemical recurrence. However, there was no evidence of disease on CT and bone scan at a prostate-specific antigen of 4.6 ng/mL. Subsequently, 18 F-DCFPyL PET/CT revealed a solitary focus of intense uptake in the right rectus abdominis muscle that was felt to represent a port-site metastasis. Histopathologic evaluation with immunostaining following ultrasound-guided needle biopsy confirmed the presence of metastatic adenocarcinoma of the prostate.
切口部位转移是前列腺癌微创肿瘤外科治疗后一种极其罕见的并发症。我们报告了一例 74 岁男性患者的病例，他接受了机器人辅助腹腔镜根治性前列腺切除术，随后进行了挽救性放疗。尽管进行了治疗，但他仍出现生化复发。然而，在前列腺特异性抗原为 4.6ng/mL 时，CT 和骨扫描均未见疾病证据。随后，18 F-DCFPyL PET/CT 显示右侧腹直肌有一个孤立的强烈摄取焦点，被认为是切口部位转移。超声引导下经皮活检后进行免疫组化的组织病理学评估证实存在前列腺腺癌的转移性肿瘤。
