Yan Tian Meng, Zuo Ya Gang
Department of Dermatology,The University of Hong Kong-Shenzhen Hospital,Shenzhen 518053,China.
Department of Dermatology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Oct 30;41(5):685-689. doi: 10.3881/j.issn.1000-503X.11698.
Bullous pemphigoid(BP)is an autoimmune blister disease caused by antibodies to the basement membrane zone.It usually exhibits tense bullae in skin and mucous membrane.BP patients can suffer from thrombosis due to hypercoagulation and/or hemorrhage due to the presence of anti-coagulation factors,which may be explained by the eosinophils,antibodies to the coagulation factors,and fibrinolytic system hyperactivity or inhibition.
大疱性类天疱疮（BP）是一种由针对基底膜带的抗体引起的自身免疫性水疱病。它通常在皮肤和黏膜上表现为紧张性水疱。BP患者可能因高凝状态而发生血栓形成，和/或因存在抗凝因子而发生出血，这可能由嗜酸性粒细胞、凝血因子抗体以及纤维蛋白溶解系统的亢进或抑制来解释。
