An Efficient Disinfectant, Composite Material {SLS@[Zn(CitH)]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens.

The [Zn(CitH)] () (CitH= citric acid), was dispersed in sodium lauryl sulphate (SLS) to form the micelle of SLS@[Zn(CitH)] (). This material was incorporated in hydrogel made by hydroxyethyl-methacrylate (HEMA), an ingredient of contact lenses, toward the formation of pHEMA@(SLS@[Zn(CitH)]) (). Samples of and were characterized by UV-Vis, H-NMR, FT-IR, FT-Raman, single crystal X-ray crystallography, X-ray fluorescence analysis, atomic absorption and TG/DTA/DSC. The antibacterial activity of - as well as of SLS against Gram-positive and and Gram-negative , and bacteria was evaluated by the means of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and inhibitory zone (IZ). showed 10 to 20-fold higher activity than against the bacteria tested. Moreover the decreases the abundance of Gram-positive microbes up to 30% () and up to 20% (PAO1) the Gram-negative ones. The noteworthy antimicrobial activity of the obtained composite suggests an effective antimicrobial additive for infection-free contact lenses.