Doornekamp Laura, GeurtsvanKessel Corine, Slobbe Lennert, Te Marvelde Merel R, Scherbeijn Sandra M J, van Genderen Perry J J, van Gorp Eric C M, Goeijenbier Marco
Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Travel Clinic, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Department of Viroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Travel Med Infect Dis. 2019 Nov-Dec;32:101511. doi: 10.1016/j.tmaid.2019.101511. Epub 2019 Nov 5.
This Dutch travel Vaccination Study (DiVeST) aimed to study adherence or compliance to Dutch travel health guidelines in travelling families and to identify risk groups to provide better advice and protection for international travellers.
Between 2016 and 2018, family members who travelled to Eastern Europe or outside Europe during the preceding year were recruited via Dutch secondary schools. The vaccination status of the travellers was assessed using questionnaires and vaccination records and hepatitis A virus antibody concentrations in dried blood spot (DBS) eluates. Subgroups of travellers with lower adherence to guidelines were identified.
Of the 246 travellers that participated in this study, 155 (63%) travelled to destinations for which the HAV vaccination was recommended. Of these 155 travellers, 56 (36%) said they visited a pre-travel clinic, and 64 of them (41%) showed a valid HAV vaccination in their vaccination records. Of the 145 travellers with available DBS eluates, anti-HAV antibodies were detected in 98 (68%) of them.
We found that adherence to travel health guidelines, in terms of HAV vaccination, was suboptimal. According to our results, specific attention should be paid to children, persons visiting friends and relatives and those who travel relatively short distances.
这项荷兰旅行疫苗接种研究（DiVeST）旨在研究旅行家庭对荷兰旅行健康指南的依从性或遵守情况，并确定风险群体，以便为国际旅行者提供更好的建议和保护。
在2016年至2018年期间，通过荷兰中学招募了前一年前往东欧或欧洲以外地区旅行的家庭成员。通过问卷调查、疫苗接种记录以及干血斑（DBS）洗脱液中的甲型肝炎病毒抗体浓度来评估旅行者的疫苗接种状况。确定了对指南依从性较低的旅行者亚组。
在参与本研究的246名旅行者中，155人（63%）前往了推荐接种甲型肝炎疫苗的目的地。在这155名旅行者中，56人（36%）表示他们去过旅行前诊所，其中64人（41%）的疫苗接种记录显示有有效的甲型肝炎疫苗接种。在145名有可用DBS洗脱液的旅行者中，98人（68%）检测到抗甲型肝炎抗体。
我们发现，在甲型肝炎疫苗接种方面，对旅行健康指南的依从性欠佳。根据我们的研究结果，应特别关注儿童、探亲访友者以及旅行距离相对较短的人。
