The Royal Marsden Hospital, London, U.K.
The Institute of Cancer Research, London, U.K.
Anticancer Res. 2019 Nov;39(11):6223-6230. doi: 10.21873/anticanres.13831.
BACKGROUND/AIM: To describe imaging features of head and neck soft-tissue sarcomas.
Patients with a diagnosis of head and neck sarcoma between 2011 and 2015 were reviewed.
There were a total of 62 patients (24 female; median age=60 years). Most common sarcomas were angiosarcoma, undifferentiated pleomorphic sarcoma and sarcoma not otherwise specified. They were most commonly located in cranial and neck superficial soft tissues. Average tumour size at presentation was 45 mm. One patient had metastasis at presentation (rhabdomyosarcoma); two had nodal disease (rhabdomyosarcoma and angiosarcoma) and two tumours contained calcification (chondrosarcoma and synovial sarcoma). Four arose after prior radiotherapy.
Unlike the more common diagnosis of squamous cell carcinoma, the majority of head and neck sarcomas present as large, solitary, superficial masses without lymph node enlargement. Identification of these features on imaging should raise suspicion of a sarcoma diagnosis, particularly in the setting of previous irradiation or genetic susceptibility.
背景/目的:描述头颈部软组织肉瘤的影像学特征。
回顾了 2011 年至 2015 年间诊断为头颈部肉瘤的患者。
共有 62 名患者(24 名女性;中位年龄=60 岁)。最常见的肉瘤为血管肉瘤、未分化多形性肉瘤和非特指性肉瘤。它们最常见于颅颈浅表软组织。就诊时的平均肿瘤大小为 45 毫米。1 名患者就诊时发生转移(横纹肌肉瘤);2 名患者发生淋巴结疾病(横纹肌肉瘤和血管肉瘤),2 个肿瘤含有钙化(软骨肉瘤和滑膜肉瘤)。4 个肿瘤是在先前放疗后发生的。
与更常见的鳞状细胞癌诊断不同,大多数头颈部肉瘤表现为大的、单发的、表浅的肿块,没有淋巴结肿大。在影像学上识别这些特征应引起对肉瘤诊断的怀疑,特别是在先前照射或遗传易感性的情况下。