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椎前间隙滑膜肉瘤可酷似恶性神经源性肿瘤:病例报告及文献复习

Synovial sarcoma in the prevertebral space can mimic malignant neurogenic neoplasm: Case report and literature review.

作者信息

Guo Yi, Lin Chong, Li Xiao-Xia, Zhou Jian-Jun, Wang Jian

机构信息

Department of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Fujian Province, China.

Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.

出版信息

Radiol Case Rep. 2023 Sep 18;18(11):4195-4201. doi: 10.1016/j.radcr.2023.08.106. eCollection 2023 Nov.

DOI:10.1016/j.radcr.2023.08.106
PMID:37753502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10518339/
Abstract

Synovial sarcoma, a rare malignant neoplasm with a poor prognosis, accounts for approximately 5%-10% of all primary soft-tissue malignancies worldwide. Typically affecting adolescents and young adults, it primarily manifests near the joints of the lower extremities. This study aimed to demonstrate that this tumor can also affect the prevertebral space. A 32-year-old male patient presented at our outpatient clinic with a 2-month history of upper limb numbness and a 1-month complaint of palpable neck mass. Imaging studies revealed a bulky, lobulated, and heterogeneous mass exhibiting heterogeneous enhancement. Furthermore, the mass caused expansion of the neuroforamen in the neck, initially suggesting a diagnosis of malignant schwannoma. However, a histopathologic examination suggested synovial sarcoma. The article provided a comprehensive review of the clinical, pathological, and radiological features of this condition. Additionally, it explored current treatment options and prognoses by referencing relevant literature.

摘要

滑膜肉瘤是一种预后较差的罕见恶性肿瘤,约占全球所有原发性软组织恶性肿瘤的5%-10%。它通常影响青少年和年轻成年人,主要发生在下肢关节附近。本研究旨在证明这种肿瘤也可累及椎前间隙。一名32岁男性患者到我们门诊就诊,有2个月上肢麻木病史,1个月来可触及颈部肿块。影像学检查显示一个体积较大、分叶状、不均匀的肿块,呈不均匀强化。此外,肿块导致颈部神经孔扩大,最初提示诊断为恶性神经鞘瘤。然而,组织病理学检查提示为滑膜肉瘤。本文全面综述了该病的临床、病理和放射学特征。此外,还通过参考相关文献探讨了当前的治疗选择和预后情况。

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本文引用的文献

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Primary synovial sarcoma of the shoulder: Case report of the "triple sign" on proton density magnetic resonance imaging.肩部原发性滑膜肉瘤:质子密度磁共振成像“三联征”病例报告
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WHO classification of soft tissue tumours 2020: An update and simplified approach for radiologists.世界卫生组织 2020 年软组织肿瘤分类:放射科医生的更新和简化方法。
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滑膜肉瘤的常规与高级 MRI 成像见解。
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Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.免疫和遗传机制在滑膜肉瘤中塑造致癌程序。
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The Effect of Resection Margin on Local Recurrence and Survival in High Grade Soft Tissue Sarcoma of the Extremities: How Far Is Far Enough?切缘对肢体高级别软组织肉瘤局部复发及生存的影响:多远才算足够?
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