Ou S M
Cancer Hospital, Zhongshan University of Medical Sciences, Guangzhou.
Zhonghua Zhong Liu Za Zhi. 1988 Jul;10(4):289-92.
From 1964 to 1984, 87 patients with soft tissue sarcoma (excluding lymphreticulum system sarcoma) in the head and neck were treated in our hospital. All were proved by pathology. The incidence rate of fibrosarcoma was the highest (36.8%), hemangiosarcoma the lowest (5.8%). There was no liposarcoma or synovial sarcoma in this group. The most frequently involved site was the area near the nasal cavity and maxillary sinus for fibrosarcoma (66%), the base of tongue for hemangiosarcoma (60%), scalp for dermatofibrosarcoma protuberans (54%), parapharyngeal space and soft tissue of the neck for neurogenic sarcoma (45%). Metastasis rate to the lymph nodes was 16-20% for rhabdomyosarcoma, hemangiosarcoma and malignant fibrohistiocyte tumor. No distant metastasis was found in dermatofibrosarcoma protuberans and malignant fibrohistiocyte tumor. Distant metastasis rate was 10-20% for the other types. Local recurrence rate was 9.1% for dermatofibrosarcoma protuberans, 88.9% for malignant fibrohistiocyte tumor, 30-66.7% for the other sarcomas. The 5- and 10-year survival rates were 20% and 0%, 37.5% and 0%, 91.6% and 91.6% for rhabdomyosarcoma, malignant fibrohistiocyte tumor and dermatofibrosarcoma protuberans. There were differences in clinical behavior for soft tissue sarcomas in the head, neck and in the trunk. Highly malignant sarcomas, such as liposarcoma, synovial sarcoma and rhabdomyosarcoma were rare in the head and neck but the low malignant sarcomas in the head and neck were 3-10 times as common as those in the trunk. Distant metastasis rate of the fibrosarcoma was 20% in head and neck and 6.7%in trunk, the 5- and 10-year survival rates were 36% and 77.9%, 25% and 73.6%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
1964年至1984年,我院共收治87例头颈部软组织肉瘤(不包括淋巴网状系统肉瘤)患者。所有病例均经病理证实。纤维肉瘤发病率最高(36.8%),血管肉瘤最低(5.8%)。本组无脂肪肉瘤或滑膜肉瘤。纤维肉瘤最常累及的部位是鼻腔和上颌窦附近区域(66%),血管肉瘤是舌根(60%),隆突性皮肤纤维肉瘤是头皮(54%),神经源性肉瘤是咽旁间隙和颈部软组织(45%)。横纹肌肉瘤、血管肉瘤和恶性纤维组织细胞瘤的淋巴结转移率为16% - 20%。隆突性皮肤纤维肉瘤和恶性纤维组织细胞瘤未发现远处转移。其他类型的远处转移率为10% - 20%。隆突性皮肤纤维肉瘤的局部复发率为9.1%,恶性纤维组织细胞瘤为88.9%,其他肉瘤为30% - 66.7%。横纹肌肉瘤、恶性纤维组织细胞瘤和隆突性皮肤纤维肉瘤的5年和10年生存率分别为20%和0%、37.5%和0%、91.6%和91.6%。头颈部与躯干的软组织肉瘤临床行为存在差异。脂肪肉瘤、滑膜肉瘤和横纹肌肉瘤等高恶性肉瘤在头颈部少见,但头颈部低恶性肉瘤的发生率是躯干的3 - 10倍。头颈部纤维肉瘤的远处转移率为20%,躯干为6.7%,其5年和10年生存率分别为36%和77.9%、25%和73.6%。(摘要截稿于250词)