Möller G, Hammarström L, Möller E, Persson U, Smith E, Waterfield D, Waterfield E
Haematologia (Budap). 1978;12(1-4):37-45.
Con A can activate cytotoxic effector cells, helper cells and suppressor cells. In all cases Con A activates polyclonally and thus the entire T cell repertoir can be revealed by Con A activation. Nylon purified T cells cannot be activated by Con A. however, in the presence of helper cells, such as adherent cells, or in the presence of serum from several species, Con A activates purified T cells. The serum factors that are responsible for Con A activation of purified T cells are present in the albumin fraction. It is suggested that Ia molecules may be responsible for the ability of Con A to activate purified T cells and a general hypothesis for T cell activation is outlined.
刀豆球蛋白A（Con A）可激活细胞毒性效应细胞、辅助细胞和抑制细胞。在所有情况下，Con A均可多克隆激活，因此通过Con A激活可揭示整个T细胞库。尼龙纯化的T细胞不能被Con A激活。然而，在辅助细胞（如黏附细胞）存在的情况下，或在几种物种的血清存在的情况下，Con A可激活纯化的T细胞。负责Con A激活纯化T细胞的血清因子存在于白蛋白组分中。有人提出，Ia分子可能是Con A激活纯化T细胞能力的原因，并概述了T细胞激活的一般假说。
