Reid M M, Saunders P W, Kernahan J
Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne.
J Clin Pathol. 1988 Aug;41(8):883-5. doi: 10.1136/jcp.41.8.883.
Over eight years, eight cases of childhood myeloproliferative disease were recognised in the northern region of England (population 3.1 million). Five were classic chronic myeloid leukaemia (CML) and the three others, forms of myeloproliferative disease. No case of juvenile CML was recognised. With the exception of CML, "adult" type myeloproliferative disease of children is underrepresented in the literature and its natural history remains unknown.
在八年时间里,英格兰北部地区(人口310万)确诊了8例儿童骨髓增殖性疾病。其中5例为典型慢性髓性白血病(CML),另外3例为其他形式的骨髓增殖性疾病。未发现青少年型CML病例。除CML外,儿童“成人”型骨髓增殖性疾病在文献中的报道较少,其自然病程仍不清楚。