Kasugai Kunio, Yamamoto Sayuri, Kawamura Yurika, Adachi Kazunori, Yamaguchi Yoshiharu, Tamura Yasuhiro, Izawa Shinya, Hijikata Yasutaka, Ebi Masahide, Funaki Yasushi, Ogasawara Naotaka, Sasaki Masato
Division of Gastroenterology, Aichi Medical University School of Medicine.
Nihon Shokakibyo Gakkai Zasshi. 2019;116(11):913-926. doi: 10.11405/nisshoshi.116.913.
Although chronic constipation is highly prevalent, its definition remains unclear. Therefore, the prevalence varies depending on reports, and the understanding of actual situations is unclear. Hence, we performed an internet survey on constipation among the Japanese general population to study the background factors and actual situations. Preliminary study on the awareness of constipation was conducted among 10000 people in which 9523 of them was asked if they had constipation at the time of the survey. In this population, 51.5% realized that they had constipation. Multivariate analysis showed the significant association of constipation to age, sex, and past histories or complications of diabetes, hemorrhoids, and cerebrovascular diseases. In a main research composed of 3000 general Japanese population, approximately 30.9% of the subjects reported the use of laxatives to treat constipation, and 43.8% of them were found to use irritant laxatives. Moreover, 67.5% of the subjects purchased laxatives at a pharmacy. The frequency of bowel movement less than 3 times per week was manifested in 36.3% of the subjects, and more than once per week in 21.4%. The percentage of hard (Bristol Stool Form Scale [BSFS] Type 1-2), normal (BSFS Type 3-5), and diarrhea stools (BSFS Type 6-7) was 33.1%, 60.0%, and 6.9%, respectively. The quality of life (QOL) of the subjects with hard and diarrhea stools evaluated by SF-8 was significantly lower than that of those with normal stools. Furthermore, the actual monthly cost for the therapeutic drugs used for treating constipation was less than 1000 yen in 75% of the subjects. Analysis of the IBS-QOL-J indicated that the ≥5000 yen payable group had the lowest satisfaction of defecation among the study groups. At present, many Japanese patients with constipation have not been receiving enough treatment for constipation. Therefore, appropriate medication by physicians as well as instruction to patients is required.
尽管慢性便秘非常普遍，但其定义仍不明确。因此，患病率因报告而异，对实际情况的了解也不清楚。于是，我们对日本普通人群进行了一项关于便秘的网络调查，以研究其背景因素和实际情况。在10000人中进行了关于便秘认知的初步研究，其中9523人在调查时被问及是否患有便秘。在这一人群中，51.5%的人意识到自己患有便秘。多因素分析显示便秘与年龄、性别以及糖尿病、痔疮和脑血管疾病的既往病史或并发症之间存在显著关联。在一项由3000名日本普通人群组成的主要研究中，约30.9%的受试者报告使用泻药治疗便秘，其中43.8%的人使用刺激性泻药。此外，67.5%的受试者在药店购买泻药。每周排便次数少于3次的受试者占36.3%，每周排便次数多于1次的受试者占21.4%。硬便（布里斯托大便分类法[BSFS]1 - 2型）、正常便（BSFS 3 - 5型）和腹泻便（BSFS
