Schöttle Daniel, Ruppelt Friederike, Schimmelmann Benno G, Karow Anne, Bussopulos Alexandra, Gallinat Jürgen, Wiedemann Klaus, Luedecke Daniel, Rohenkohl Anja Christine, Huber Christian G, Bock Thomas, Lambert Martin
Psychosis Centre, Department of Psychiatry and Psychotherapy, University Centre of Psychosocial Medicine, Medical Center Hamburg-Eppendorf, Hamburg, Germany.
University Hospital of Child and Adolescent Psychiatry, University of Bern, Bern, Switzerland.
Front Psychiatry. 2019 Oct 24;10:736. doi: 10.3389/fpsyt.2019.00736. eCollection 2019.
The ACCESS treatment model offers assertive community treatment (ACT) embedded in an integrated care program to patients with severe psychotic disorders. Compared to standard care, it proved to be more effective in terms of service disengagement and other outcomes in patients with psychotic disorders over 12, 24, and 48 months. Many patients with severe mental disorders experience involuntary admissions which can be potentially traumatic. In this study, we assessed the effect of ACT on reducing involuntary admissions over an observation period of 4 years. One hundred seventy-one patients treated in ACCESS were included in this study. The primary outcome was rate of involuntary admissions during 48 months. Secondary outcomes were differences between those with and without involuntary admissions in the 2 years prior to ACCESS regarding change of psychopathology, severity of illness, psychosocial functioning, quality of life, satisfaction with care, medication non-adherence, and service-disengagement. Of 171 patients, 58 patients (33.9%) were involuntarily admitted to hospital in the past 2 years before entry. During the 4 years of treatment, 16 patients (9.4%) were involuntarily admitted to hospital which was a significantly lower rate compared to the 2 years before inclusion in ACCESS (p < .001). Comparing the two groups, larger improvements in severity of illness (p = .004) and functional status (p = .043) were detected in the group with no history of involuntary admissions. At 4-year follow-up, of the remaining patients, 69.2% (n = 81) were full adherent (p < .001), compared to 18.9% (n = 31) at baseline with no differences between the two groups over the study period (p = .25). Over 4 years, only 13 patients (13.2%) were service-disengaged due to non-practical reasons. In this long-term study, we were able to demonstrate a reduction in involuntary admissions in four treatment years compared to the 2 years prior to admission to the ACCESS model in patients with severe and mostly multiphase schizophrenia spectrum disorders and affective disorders with psychotic features. This may help prevent patients from suffering from a potentially traumatic experience during treatment in the psychiatric system. www.ClinicalTrials.gov, identifier NCT01888627.
ACCESS治疗模式为患有严重精神障碍的患者提供了融入综合护理计划的积极社区治疗(ACT)。与标准护理相比,在12个月、24个月和48个月的时间里,它在精神障碍患者的服务脱离及其他预后方面被证明更有效。许多严重精神障碍患者会经历非自愿住院,这可能具有潜在的创伤性。在本研究中,我们评估了ACT在4年观察期内对减少非自愿住院的效果。本研究纳入了171名在ACCESS接受治疗的患者。主要结局是48个月内的非自愿住院率。次要结局是在进入ACCESS之前的2年里,有非自愿住院史和无此病史的患者在精神病理学变化、疾病严重程度、心理社会功能、生活质量、护理满意度、药物不依从性和服务脱离方面的差异。在171名患者中,58名患者(33.9%)在入组前的过去2年里曾非自愿住院。在4年的治疗期间,16名患者(9.4%)非自愿住院,这一比率显著低于纳入ACCESS之前的2年(p <.001)。比较两组,在无非自愿住院史的组中,疾病严重程度(p =.004)和功能状态(p =.043)有更大改善。在4年随访时,其余患者中,69.2%(n = 81)完全依从(p <.001),而基线时为18.9%(n = 31),两组在研究期间无差异(p =.25)。在4年时间里,只有13名患者(13.2%)因不实际的原因脱离服务。在这项长期研究中,我们能够证明,与进入ACCESS模式之前的2年相比,在4年治疗期内,患有严重且大多为多相性精神分裂症谱系障碍和伴有精神病性特征的情感障碍的患者非自愿住院率有所降低。这可能有助于防止患者在精神科系统治疗期间遭受潜在的创伤经历。ClinicalTrials.gov,标识符NCT01888627。