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天冬氨酸消旋作用在未萌出及多生牙法医牙科学中的应用

Application to forensic odontology of aspartic acid racemization in unerupted and supernumerary teeth.

作者信息

Ogino T, Ogino H

机构信息

Department of Oral Surgery, Tokyo Women's Medical College, Japan.

出版信息

J Dent Res. 1988 Oct;67(10):1319-22. doi: 10.1177/00220345880670101501.

Abstract

Racemization of aspartic acid in dentin protein during the human lifetime progresses with age. The extent of racemization of aspartic acid in coronal dentin of normal permanent teeth can be used in forensic odontology to estimate the age of an individual at the time of death (Ogino et al., 1985). A series of experiments was conducted with dentin separated from unerupted and supernumerary teeth of various ages in an attempt to evaluate the advantages and limitations of this age-estimation method. The current study on nine tooth specimens showed that some unerupted permanent teeth with normal-sized and -shaped crowns (impacted third molar, canine, and incisor) could be used to estimate the age of individuals at the time of death within +/- 4 years. However, supernumerary teeth (mesiodens, paramolar) with extremely tiny (length of crown: 4 approximately 5 mn) and abnormally shaped crowns could not be used for analysis. In such cases, the estimated age of individuals analyzed by the racemization method deviated considerably from their actual age.

摘要

人一生中牙本质蛋白中天冬氨酸的消旋化随年龄增长而进展。正常恒牙冠部牙本质中天冬氨酸的消旋化程度可用于法医牙科学中估计个体死亡时的年龄(小杉等人,1985年)。为了评估这种年龄估计方法的优缺点,对从不同年龄未萌出和多生牙中分离出的牙本质进行了一系列实验。目前对九个牙齿标本的研究表明,一些冠部大小和形状正常的未萌出恒牙(阻生第三磨牙、尖牙和切牙)可用于估计个体死亡时的年龄,误差在正负4年之内。然而,冠部极小(冠长:约4至5毫米)且形状异常的多生牙(正中牙、磨牙旁牙)不能用于分析。在这种情况下,通过消旋化方法分析的个体估计年龄与其实际年龄有很大偏差。

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