Pearson R D
Med Hypotheses. 1979 Dec;5(12):1297-303. doi: 10.1016/0306-9877(79)90097-5.
Immunologists have long suspected that maintenance of pregnancy (viable placentation) is contingent upon the suppressed maternal immune response. Curiously, it has never been suggested that the termination of pregnancy at term might in some way be triggered by the un-blocking of this maternal immune suppression. It is the hypothesis of this paper that maintenance and termination of pregnancy are contravening expressions of a maternal-fetal immunologic regulatory response. The role of the prostaglandins in parturition, and the immune response, is discussed.
免疫学家长期以来一直怀疑，维持妊娠（成功着床）取决于母体免疫反应的抑制。奇怪的是，从未有人提出足月妊娠的终止可能在某种程度上是由这种母体免疫抑制的解除所触发的。本文的假设是，妊娠的维持和终止是母胎免疫调节反应的相互矛盾的表现。本文还讨论了前列腺素在分娩和免疫反应中的作用。
