Shandong Key Laboratory of TCM Quality Control Technology, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250014, China.
Mikrochim Acta. 2019 Nov 11;186(12):761. doi: 10.1007/s00604-019-3932-5.
Metal-organic coordination polymer beads (MOCBs) are described for use as a sorbent for solid-phase extraction of chlorophenoxy herbides. By applying regulation of Co(II) ions, micro-sized monodisperse MOCBs were obtained through the microwave heating. The MOCBs-based method displays excellent extraction efficiency towards chlorophenoxy herbicides, specifically of 2-chlorophenoxyacetic acid, 4-chlorophenoxyacetic acid, 4-chloromethylphenoxyacetic acid, 2,4-dichlorophenoxyacetic acid, 2,4,5-trichlorophenoxyacetic acid and 2-(2,4-dichlorophenoxy)propionic acid. Following extraction, the herbicides were eluted with 8% formic acid in methanol and quantified by HPLC. The method, when applied to analyze spiked cereals, exhibits a wide linear range (from 0.6 to 1000 ng g) and low limits of quantification (ranging from 0.10 to 0.25 ng g). For a single column, the inter-day and intra-day precisions, expressed as the relative standard deviation are in the range of 2.5-6.8%. The batch-to-batch reproducibility (for n = 3) is <4.6%. For spiked cereal samples, relative recoveries are very good (90.3-102.3%, for n = 4). The extraction efficiency of MOCBs remains unchanged after reusing for 40 times. Graphical abstractSchematic presentation of Co(II)-doped metal-organic coordination polymer beads (Co(II)@MOCB) using for solid-phase extraction (SPE).
金属有机配位聚合物珠（MOCB）被描述为用于固相萃取氯苯氧类除草剂的吸附剂。通过调控 Co(II)离子，通过微波加热得到了微尺寸单分散的 MOCB。MOCB 基方法对氯苯氧类除草剂表现出优异的萃取效率，特别是 2-氯苯氧乙酸、4-氯苯氧乙酸、4-氯甲基苯氧乙酸、2,4-二氯苯氧乙酸、2,4,5-三氯苯氧乙酸和 2-（2,4-二氯苯氧）丙酸。萃取后，用 8%甲酸甲醇洗脱，HPLC 定量。该方法应用于分析加标谷物时，具有较宽的线性范围（0.6-1000ng g）和较低的定量限（0.10-0.25ng g）。对于单个色谱柱，日间和日内精密度（表示为相对标准偏差）在 2.5-6.8%范围内。批间重现性（n=3）<4.6%。对于加标谷物样品，相对回收率非常好（90.3-102.3%，n=4）。MOCB 经重复使用 40 次后，萃取效率保持不变。
