Khan Z U, Randhawa H S, Kowshik T, Gaur S N, de Vries G A
Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, India.
J Med Vet Mycol. 1988 Jun;26(3):145-51.
The repeated occurrence of Sporotrichum pruinosum, demonstrated by direct microscopy and culture, is reported from the respiratory tract of three patients who complained of cough, expectoration of sputum, dyspnoea and occasional pyrexia. This observation coupled with the presence of immediate, type I, cutaneous hypersensitivity against S. pruinosum in two of the patients and the ability of the fungus to incite lesions in experimentally infected mice supported an etiologic relationship between the fungus and the patients' symptoms. The macroscopic and microscopic characters of one of the clinical isolates of S. pruinosum are briefly described. It is suggested that the isolation of S. pruinosum from clinical specimens should not be regarded as of no etiologic significance without careful clinical and laboratory evaluation of the patient.
通过直接显微镜检查和培养证实，在三名主诉咳嗽、咳痰、呼吸困难和偶尔发热的患者呼吸道中反复出现粉状孢子丝菌。这一观察结果，再加上其中两名患者对粉状孢子丝菌存在速发型I型皮肤超敏反应，以及该真菌在实验感染小鼠中引发病变的能力，支持了该真菌与患者症状之间的病因学关系。简要描述了粉状孢子丝菌的一株临床分离株的宏观和微观特征。建议在对患者进行仔细的临床和实验室评估之前，不应将从临床标本中分离出粉状孢子丝菌视为无病因学意义。
