Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Netherlands Institute for Health Services Research (NIVEL), Utrecht, The Netherlands.
Eur J Public Health. 2020 Jun 1;30(3):479-484. doi: 10.1093/eurpub/ckz201.
Early detection and treatment of cardiometabolic diseases (CMD) in high-risk patients is a promising preventive strategy to anticipate the increasing burden of CMD. The Dutch guideline 'the prevention consultation' provides a framework for stepwise CMD risk assessment and detection in primary care. The aim of this study was to assess the outcome of this program in terms of newly diagnosed CMD.
A cohort study among 30 934 patients, aged 45-70 years without known CMD or CMD risk factors, who were invited for the CMD detection program within 37 general practices. Patients filled out a CMD risk score (step 1), were referred for additional risk profiling in case of high risk (step 2) and received lifestyle advice and (pharmacological) treatment if indicated (step 3). During 1-year follow-up newly diagnosed CMD, prescriptions and abnormal diagnostic tests were assessed.
Twelve thousand seven hundred and thirty-eight patients filled out the risk score of which 865, 6665 and 5208 had a low, intermediate and high CMD risk, respectively. One thousand seven hundred and fifty-five high-risk patients consulted the general practitioner, in 346 of whom a new CMD was diagnosed. In an additional 422 patients a new prescription and/or abnormal diagnostic test were found.
Implementation of the CMD detection program resulted in a new CMD diagnosis in one-fifth of high-risk patients who attended the practice for completion of their risk profile. However, the potential yield of the program could be higher given the considerable number of additional risk factors-such as elevated glucose, blood pressure and cholesterol levels-found, requiring active follow-up and presumably treatment in the future.
在高危患者中早期发现和治疗心脏代谢疾病(CMD)是一种有前途的预防策略,可以预见 CMD 负担的增加。荷兰指南“预防咨询”为初级保健中逐步进行 CMD 风险评估和检测提供了框架。本研究旨在评估该计划在新诊断 CMD 方面的结果。
一项队列研究纳入了 30934 名年龄在 45-70 岁之间、无已知 CMD 或 CMD 危险因素的患者,这些患者在 37 家普通诊所受邀参加 CMD 检测计划。患者填写 CMD 风险评分(第 1 步),如果风险较高,则被转介进行额外的风险分析(第 2 步),并在有必要时接受生活方式建议和(药物)治疗(第 3 步)。在 1 年的随访期间,评估新诊断的 CMD、处方和异常诊断测试。
12738 名患者填写了风险评分,其中 865、6665 和 5208 名患者的 CMD 风险分别为低、中、高。1755 名高危患者咨询了全科医生,其中 346 名患者新诊断出 CMD。在另外 422 名患者中,发现了新的处方和/或异常诊断测试。
实施 CMD 检测计划导致五分之一参加实践以完成风险评估的高危患者中诊断出新的 CMD。然而,鉴于发现了相当数量的其他风险因素(如血糖、血压和胆固醇水平升高),需要积极随访并可能在未来进行治疗,该计划的潜在效果可能更高。