噻吗洛尔的降压作用及其局部血管作用

Pressure lowering effect of timolol with reference to its topical vascular action.

作者信息

Cristini G, Giovannini A

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Oct;211(4):325-8. doi: 10.1007/BF00414691.

Abstract

The hemodynamic effect of timolol maleate in open angle glaucoma was studied rheo-oculographically. Increase in the ocular pulse which reaches maximal amplification 2 h after the instillation of the drug was observed. The maximal pressure lowering effect appeared 3 h after instillation, as if the hemodynamic effect were the trigger for the pressure lowering effect.

摘要

采用眼血流图法研究了马来酸噻吗洛尔对开角型青光眼的血流动力学效应。观察到滴眼后2小时眼动脉搏动增强至最大幅度。滴眼后3小时出现最大降压效果，血流动力学效应似乎是降压效应的触发因素。