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一种用于评估正常成年男性排尿储备的无创尿动力学测试原型。

A prototype non-invasive urodynamic test to estimate voiding reserve in normal adult males.

作者信息

Shoukry Shafik, Elmissiry Mostafa, Abulfotooh Ahmed, Moussa Ahmed, Mahfouz Wally, Dawood Waleed, Abdel-Karim Aly, Hassouna Mohamed

机构信息

Section of Voiding Dysfunction and Urodynamics, Department of Urology, Alexandria University, Alexandria, Egypt.

出版信息

Arab J Urol. 2019 Aug 29;17(4):251-256. doi: 10.1080/2090598X.2019.1649892. eCollection 2019.

Abstract

: To propose a prototype non-invasive test to estimate voiding reserve in normal adult men; identifying its feasibility, limitations, and initial results. : In all, 30 adult healthy male volunteers aged <40 years were included in the study. Initial free uroflowmetry was done with post-void residual urine volume (PVR) assessment using ultrasonography. The men were later asked to void into a uroflowmeter through a condom catheter attached to the glans penis and connected to an outflow tube with specific vertical heights (10, 20, 30, 40, 50 and 60 cm) on different days. The mean maximum urinary flow rate (Q) and PVR at each height were compared with the Q and PVR at the initial free uroflowmetry. The maximum height at which the Q and PVR remained normal was considered the normal voiding reserve for that age group. : All the men completed the study without any complications. At zero level, the mean Q was 27.6 mL/s, which then dropped gradually to reach 17.8 mL/s at 60 cm, where still 83% of the men had a normal Q. The PVR was nil at zero level and started to exceed the normal range at 50 and 60 cm height (58 and 65.7 mL, respectively). So, the maximum height resistance at which the men could have a normal Q and normal PVR was 40 cm. : The use of the tube height-resistance test to assess voiding reserve is feasible, non-invasive and has no complications. A 40-cm height resistance can be considered a reference level that a young adult male should be tested against to estimate his voiding reserve. : NPV: negative predictive value; PQ: maximum detrusor pressure at maximum urinary flow; PPV: positive predictive value; PVR: post-void residual urine volume; ROC: receiver operating characteristic.

摘要

目的

提出一种用于评估正常成年男性排尿储备的非侵入性测试原型;确定其可行性、局限性和初步结果。

方法

本研究共纳入30名年龄<40岁的成年健康男性志愿者。首先进行自由尿流率测定,并使用超声评估排尿后残余尿量(PVR)。随后,让这些男性在不同日期通过连接在阴茎头的避孕套导管将尿液排入尿流计,该导管连接到具有特定垂直高度(10、20、30、40、50和60厘米)的流出管。将每个高度下的平均最大尿流率(Q)和PVR与初始自由尿流率测定时的Q和PVR进行比较。Q和PVR保持正常的最大高度被视为该年龄组的正常排尿储备。

结果

所有男性均顺利完成研究,无任何并发症。在零高度时,平均Q为27.6毫升/秒,然后逐渐下降,在60厘米高度时降至17.8毫升/秒,此时仍有83%的男性Q正常。PVR在零高度时为零,在50和60厘米高度时开始超过正常范围(分别为58和65.7毫升)。因此,男性能够保持正常Q和正常PVR的最大高度阻力为40厘米。

结论

使用管高度阻力测试评估排尿储备是可行的、非侵入性的且无并发症。40厘米的高度阻力可被视为一个参考水平,年轻成年男性应以此为标准进行测试以评估其排尿储备。

缩写词

NPV:阴性预测值;PQ:最大尿流率时的最大逼尿肌压力;PPV:阳性预测值;PVR:排尿后残余尿量;ROC:受试者工作特征曲线

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4222/6830265/8ba36db4dfca/TAJU_A_1649892_F0001_OC.jpg

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