Kim Song Yee, Jeong Su Jin, Lee Jin Gu, Park Moo Suk, Paik Hyo Chae, Na Sungwon, Kim Jeongmin
Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Acute Crit Care. 2018 Nov;33(4):206-215. doi: 10.4266/acc.2018.00360. Epub 2018 Nov 30.
Since the first successful lung transplantation in 1983, there have been many advances in the field. Nevertheless, the latest data from the International Society for Heart and Lung Transplantation revealed that the risk of death from transplantation is 9%. Various aspects of postoperative management, including mechanical ventilation, could affect intensive care unit stay, hospital stay, and immediate postoperative morbidity and mortality. Complications such as reperfusion injury, graft rejection, infection, and dehiscence of anastomosis increase fatal adverse side effects immediately after surgery. In this article, we review the possible immediate complications after lung transplantation and summarize current knowledge on prevention and treatment.
自1983年首次成功进行肺移植以来,该领域已取得诸多进展。然而,国际心肺移植学会的最新数据显示,移植导致的死亡风险为9%。术后管理的各个方面,包括机械通气,都可能影响重症监护病房停留时间、住院时间以及术后早期的发病率和死亡率。诸如再灌注损伤、移植物排斥反应、感染和吻合口裂开等并发症会在术后立即增加致命的不良副作用。在本文中,我们回顾了肺移植后可能出现的早期并发症,并总结了目前关于预防和治疗的知识。