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“血压可能明天就会要了你的命,但 HIV 能给你时间”:马拉维艾滋病毒感染者和高血压患者的疾病认知和治疗体验。

'Blood pressure can kill you tomorrow, but HIV gives you time': illness perceptions and treatment experiences among Malawian individuals living with HIV and hypertension.

机构信息

Department of Medicine, University of California Los Angeles, David Geffen School of Medicine, Le Conte Ave, Los Angeles, CA, USA.

Partners in Hope, (Area 36/Plot 8), Lilongwe, Malawi.

出版信息

Health Policy Plan. 2019 Nov 1;34(Supplement_2):ii36-ii44. doi: 10.1093/heapol/czz112.

Abstract

Non-communicable diseases like hypertension are increasingly common among individuals living with HIV in low-resource settings. The prevalence of hypertension among people with HIV in Malawi, e.g. has been estimated to be as high as 46%. However, few qualitative studies have explored the patient experience with comorbid chronic disease. Our study aimed to address this gap by using the health belief model (HBM) to examine how comparative perceptions of illness and treatment among participants with both HIV and hypertension may affect medication adherence behaviours. We conducted semi-structured interviews with 75 adults with HIV and hypertension at an urban clinic in Lilongwe, Malawi. Questions addressed participants' experiences with antiretroviral and antihypertensive medications, as well as their perspectives on HIV and hypertension as illnesses. Interviews were performed in Chichewa, transcribed, translated into English and analysed using ATLAS.ti. Deductive codes were drawn from the HBM and interview guide, with inductive codes added as they emerged from the data. Self-reported medication adherence was much poorer for hypertension than HIV, but participants saw hypertension as a disease at least as concerning as HIV-primarily due to the perceived severity of hypertension's consequences and participants' limited ability to anticipate them compared with HIV. Differences in medication adherence were attributed to the high costs of antihypertensive medications relative to the free availability of antiretroviral therapy, with other factors like lifestyle changes and self-efficacy also influencing adherence practices. These findings demonstrate how participants draw on past experiences with HIV to make sense of hypertension in the present, and suggest that although patients are motivated to control their hypertension, they face individual- and system-level obstacles in adhering to treatment. Thus, health policies and systems seeking to provide integrated care for HIV and hypertension should be attentive to the complex illness experiences of individuals living with these diseases.

摘要

在资源匮乏的环境中,生活在 HIV 中的个体中越来越常见的非传染性疾病,如高血压。例如,在马拉维,HIV 患者中高血压的患病率估计高达 46%。然而,很少有定性研究探讨合并慢性疾病的患者体验。我们的研究旨在通过使用健康信念模型(HBM)来解决这一差距,该模型检查了参与者对 HIV 和高血压的比较疾病和治疗观念如何影响药物依从行为。我们在马拉维利隆圭的一家城市诊所对 75 名 HIV 和高血压患者进行了半结构式访谈。问题涉及参与者对抗逆转录病毒和抗高血压药物的经验,以及他们对 HIV 和高血压作为疾病的看法。访谈是用奇契瓦语进行的,转录,翻译成英文,然后用 ATLAS.ti 进行分析。从 HBM 和访谈指南中得出了演绎代码,并根据数据中出现的情况添加了归纳代码。自我报告的药物依从性对于高血压比 HIV 差得多,但参与者认为高血压是一种疾病,至少与 HIV 一样令人担忧-主要是由于高血压后果的感知严重性以及参与者与 HIV 相比,对其的预测能力有限。药物依从性的差异归因于抗高血压药物的高成本与抗逆转录病毒治疗的免费可用性之间的差异,其他因素,如生活方式的改变和自我效能也会影响药物依从性。这些发现表明参与者如何利用过去的 HIV 经验来理解现在的高血压,并表明尽管患者有动力控制自己的高血压,但他们在遵守治疗方面面临个人和系统层面的障碍。因此,寻求为 HIV 和高血压提供综合护理的卫生政策和系统应该关注患有这些疾病的个人的复杂疾病体验。

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