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床旁超声在小儿急性呼吸窘迫综合征中的作用:其应用的新证据

The role of point-of-care ultrasound in pediatric acute respiratory distress syndrome: emerging evidence for its use.

作者信息

Potter Samantha K, Griksaitis Michael J

机构信息

Pediatric Intensive Care Unit, Southampton Children's Hospital, Southampton, UK.

Faculty of Medicine, University of Southampton, Southampton, UK.

出版信息

Ann Transl Med. 2019 Oct;7(19):507. doi: 10.21037/atm.2019.07.76.

Abstract

Pediatric acute respiratory distress syndrome (PARDS) remains an important cause of significant morbidity and mortality. The 2015 PALICC definition of PARDS requires chest imaging to diagnose the presence of new pulmonary infiltrate(s). Traditionally chest radiography or computerised tomography have been used. However, these carry the limitations of exposure to ionizing radiation, need to transfer the critically unwell child, lag-time with clinical correlation and lack of immediate results. The use of point of care ultrasound (POCUS) has been well established in adult emergency medicine and critical care. Furthermore, the adult literature clearly demonstrates that lung POCUS is a safe and validated tool, which is highly sensitive and specific when compared to chest radiography for differentiating the causes of respiratory failure, including ARDS. Whilst pediatric specific data is limited, it has been shown that the signs seen in adults are reproducible in critically ill neonates and children. Furthermore, the numerous benefits of POCUS in the paediatric setting are compelling and include lack of ionizing radiation, immediate feedback, promoting time at the bedside of the critically unwell child, and ease of serial assessments. This review article presents the emerging evidence demonstrating that lung POCUS can be used not only to support the diagnosis of pediatric ARDS, but also to assess for complications, monitor progression and thus guide management. We hope it will stimulate much needed collaborative research into this exciting field of imaging and its applications to PARDS and beyond.

摘要

小儿急性呼吸窘迫综合征(PARDS)仍然是导致严重发病和死亡的重要原因。2015年PALICC对PARDS的定义要求通过胸部影像学检查来诊断新出现的肺部浸润情况。传统上一直使用胸部X线摄影或计算机断层扫描。然而,这些方法存在暴露于电离辐射、需要转运病情危重的儿童、与临床关联存在延迟以及缺乏即时结果等局限性。床旁超声(POCUS)在成人急诊医学和重症监护中已得到广泛应用。此外,成人文献清楚地表明,肺部POCUS是一种安全且经过验证的工具,与胸部X线摄影相比,在鉴别包括ARDS在内的呼吸衰竭病因时具有高度敏感性和特异性。虽然儿科方面的具体数据有限,但已表明在成人中看到的征象在危重新生儿和儿童中具有可重复性。此外,POCUS在儿科环境中的众多益处令人信服,包括无电离辐射、即时反馈、增加在病情危重儿童床边的时间以及便于进行系列评估。这篇综述文章展示了新出现的证据,表明肺部POCUS不仅可用于支持小儿ARDS的诊断,还可用于评估并发症、监测病情进展并因此指导治疗。我们希望它将激发对这个令人兴奋的成像领域及其在PARDS及其他方面应用的急需的合作研究。

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