结核病的药物治疗。
Treatment of Drug-Susceptible Tuberculosis.
机构信息
Department of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, Box 0111, 513 Parnassus Avenue, San Francisco, CA 94117, USA.
Department of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, Box 0841 MD, 1001 Potrero Avenue, 5J6, San Francisco, CA 94110, USA.
出版信息
Clin Chest Med. 2019 Dec;40(4):763-774. doi: 10.1016/j.ccm.2019.07.006.
Mycobacterium tuberculosis is a major public health concern and requires prompt treatment. Goals of treatment include curing the individual patient and protecting the community from ongoing tuberculosis transmission. To achieve durable cure, regimens must include multiple agents given concurrently and in a manner to ensure completion of therapy. This article focuses on preferred regimens of drug-susceptible tuberculosis under current guidelines by the American Thoracic Society, Centers for Disease Control and Prevention, and Infectious Diseases Society of America and World Health Organization. In addition, topics including patient centered care, poor treatment outcomes, and adverse effects are also discussed.
结核分枝杆菌是一个主要的公共卫生关注点，需要及时治疗。治疗的目标包括治愈个体患者和保护社区免受持续的结核传播。为了实现持久的治愈，方案必须包括多种同时给予的药物，并确保完成治疗。本文重点介绍了美国胸科学会、疾病控制与预防中心、传染病学会和世界卫生组织现行指南下耐多药结核病的首选方案。此外，还讨论了以患者为中心的护理、治疗效果不佳和不良反应等主题。
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