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围手术期实验室检查在接受脊柱侧弯融合手术的儿科患者中的应用

Utility of Perioperative Laboratory Tests in Pediatric Patients Undergoing Spinal Fusion for Scoliosis.

作者信息

Adams Alexander J, Cahill Patrick J, Flynn John M, Sankar Wudbhav N

机构信息

Division of Orthopaedic Surgery, the Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, 2nd Floor Wood Building, Philadelphia, PA, 19104, USA.

Division of Orthopaedic Surgery, the Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, 2nd Floor Wood Building, Philadelphia, PA, 19104, USA.

出版信息

Spine Deform. 2019 Nov;7(6):875-882. doi: 10.1016/j.jspd.2019.02.009.

Abstract

STUDY DESIGN

Retrospective comparative study.

OBJECTIVES

We aimed to characterize the frequency of perioperative laboratory tests for posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS) and to assess whether test results affected clinical management.

SUMMARY OF BACKGROUND DATA

Perioperative laboratory tests for PSF including complete blood count, coagulation laboratory tests, basic metabolic panels (BMPs), and type and screen, are commonly ordered based on providers' discretion or existing order sets. Studies have shown unnecessary laboratory tests as financially and physically costly in adults; however, no studies have examined the necessity of common perioperative laboratory tests in pediatric spinal deformity surgery.

METHODS

Retrospective review of patients aged 10-18 years who underwent PSF for AIS at our center in the past three years. The clinical utility of perioperative laboratory tests was assessed based on detected incidence of anemia, blood transfusions, hematology/endocrinology/nephrology consultations, insulin administration, and postponed/canceled surgeries.

RESULTS

A total of 234 patients were included (mean age 14.4 ± 1.8 years, 75% female). Of 105 (44.9%) patients with preoperative coagulation laboratory tests, 21 (20%) had abnormal results; however, none had subsequent hematology consultations or canceled/postponed surgeries. Postoperatively, only 5 (2.1%) patients and 30 (12.8%) patients had hemoglobin values less than 8 g/dL on postoperative day (POD) 1 and 2, respectively. Multivariate analysis identified POD1 hemoglobin ≤9.35 g/dL as the only predictor of hemoglobin <8 g/dL on POD2. Overall, there were 8 (3.4%) indicated blood transfusions postoperatively. Costs of unnecessary laboratory tests averaged $95.27 (range $49.72 to $240.27) per patient.

CONCLUSIONS

Many perioperative laboratory orders may be unnecessary in pediatric spinal deformity surgery, subjecting patients to extraneous costs and needlesticks. In particular, preoperative coagulation laboratory tests, perioperative BMPs, and additional postoperative CBCs for those with hemoglobin >9.35 on POD1 may not be warranted.

LEVEL OF EVIDENCE

Level III, retrospective cohort study.

摘要

研究设计

回顾性比较研究。

目的

我们旨在描述青少年特发性脊柱侧凸(AIS)后路脊柱融合术(PSF)围手术期实验室检查的频率,并评估检查结果是否影响临床管理。

背景数据总结

PSF的围手术期实验室检查包括全血细胞计数、凝血实验室检查、基础代谢指标(BMP)以及血型鉴定和筛查,通常根据医疗服务提供者的判断或现有医嘱集进行开具。研究表明,在成人中不必要的实验室检查在经济和身体方面代价高昂;然而,尚无研究探讨小儿脊柱畸形手术中常见围手术期实验室检查的必要性。

方法

回顾性分析过去三年在我们中心接受AIS后路脊柱融合术的10至18岁患者。根据贫血、输血、血液学/内分泌学/肾脏病会诊、胰岛素给药以及手术延期/取消的检出率评估围手术期实验室检查的临床效用。

结果

共纳入234例患者(平均年龄14.4±1.8岁,75%为女性)。在105例(44.9%)术前进行凝血实验室检查的患者中,21例(20%)结果异常;然而,无人随后进行血液学会诊或取消/延期手术。术后,分别只有5例(2.1%)和30例(12.8%)患者在术后第1天(POD1)和第2天血红蛋白值低于8 g/dL。多因素分析确定POD1血红蛋白≤9.35 g/dL是POD2时血红蛋白<8 g/dL的唯一预测因素。总体而言,术后有8例(3.4%)患者接受了指定输血。不必要实验室检查的费用平均每位患者95.27美元(范围49.72美元至240.27美元)。

结论

小儿脊柱畸形手术中许多围手术期实验室检查医嘱可能不必要,会使患者承受额外费用和针刺风险。特别是,术前凝血实验室检查、围手术期BMP以及POD1时血红蛋白>9.35的患者术后额外的全血细胞计数检查可能没有必要。

证据水平

三级,回顾性队列研究。

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