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评估股骨干骨折小儿患者围手术期常规实验室检查的必要性。

Assessing the Need for Common Perioperative Laboratory Tests in Pediatric Patients With Femoral Shaft Fractures.

作者信息

Adams Alexander J, Baldwin Keith D, Arkader Alexandre, Sankar Wudbhav N

机构信息

Division of Orthopaedic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA.

出版信息

J Pediatr Orthop. 2019 Jul;39(6):e456-e461. doi: 10.1097/BPO.0000000000001362.

Abstract

BACKGROUND

Femoral shaft fractures are a common cause for hospital admission and surgery in pediatric patients, and laboratory studies are often ordered for historical concerns of excessive bleeding. Recent literature has challenged these assumptions, and unnecessary testing causes undue pain and costs in children. No previous studies have offered evidence-based recommendations for perioperative laboratories in isolated pediatric femoral shaft fractures.

METHODS

We retrospectively reviewed all patients presenting with femoral shaft fractures at our pediatric trauma center between 2013 and 2017. Patients with multitrauma injuries, metabolic/neuromuscular diseases, or intensive care unit stays were excluded. Necessity of laboratory tests was determined by rates of anemia, blood transfusions, specialist consultations, and delayed surgeries. Ordering patterns were recorded, with cost estimation based on Healthcare Bluebook.

RESULTS

We reviewed 95 patients (mean age, 7.9±4.8 y; 70 males). Treatments included elastic nails (33/95, 34.7%), reamed intramedullary nails (24/95, 25.3%), plates/screws (12/95, 12.6%), and spica casting (26/95, 27.4%). Of 32 patients with preoperative coagulation laboratories, 11 were abnormal; however none resulted in hematology consultations or procedure delays. Seventy-five patients (78.9%) and 15 patients (15.8%) had complete blood counts preoperatively and postoperative day 1, respectively. Four patients (4.2%) had hemoglobin<8 g/dL postoperatively, however, there were no perioperative blood transfusions. Of these 4, 3 underwent either reamed intramedullary nails or open reduction internal fixation with plates/screws. Twenty-six patients (27.4%) had preoperative basic metabolic panels that did not alter medical care. On the basis of our criteria, over 72% of laboratories appeared unnecessary, with a total potential cost of $8567. Over 80% of orders were from the emergency department by residents or attending physicians.

CONCLUSIONS

Perioperative laboratory orders may be unnecessary in most isolated pediatric femoral shaft fractures, subjecting patients to extraneous costs, and associated pain. However, laboratories may be justified based on clinical circumstances or for older patients treated with reamed nails or plates/screws. Evidence-based recommendations for perioperative laboratory orders offer the potential to improve quality and value and minimize harm in pediatric orthopaedic trauma.

LEVEL OF EVIDENCE

Level III-retrospective comparative study (therapeutic).

摘要

背景

股骨干骨折是儿科患者住院和手术的常见原因,出于对出血过多的既往担忧,常常会安排实验室检查。最近的文献对这些假设提出了质疑,不必要的检查给儿童带来了不必要的痛苦和费用。既往没有研究针对单纯性儿科股骨干骨折围手术期实验室检查提供基于证据的建议。

方法

我们回顾性分析了2013年至2017年间在我们儿科创伤中心就诊的所有股骨干骨折患者。排除有多发伤、代谢/神经肌肉疾病或入住重症监护病房的患者。根据贫血发生率、输血情况、专科会诊情况和手术延迟情况来确定实验室检查的必要性。记录检查申请模式,并根据医疗保健蓝皮书进行成本估算。

结果

我们分析了95例患者(平均年龄7.9±4.8岁;男性70例)。治疗方法包括弹性髓内钉(33/95,34.7%)、扩髓髓内钉(24/95,25.3%)、钢板/螺钉(12/95,12.6%)和髋人字石膏固定(26/95,27.4%)。在32例术前行凝血功能检查的患者中,11例异常;然而,没有一例导致血液科会诊或手术延迟。分别有75例患者(78.9%)和15例患者(15.8%)在术前和术后第1天进行了血常规检查。4例患者(4.2%)术后血红蛋白<8 g/dL,然而,围手术期均未输血。在这4例患者中,3例接受了扩髓髓内钉或钢板/螺钉切开复位内固定术。26例患者(27.4%)术前行基础代谢指标检查,但这些检查并未改变医疗方案。根据我们的标准,超过72%的实验室检查似乎是不必要的,潜在总成本为8567美元。超过80%的检查申请来自急诊科的住院医师或主治医师。

结论

在大多数单纯性儿科股骨干骨折中,围手术期实验室检查可能是不必要的,这会让患者承受额外的费用和相关痛苦。然而,根据临床情况或对于接受扩髓髓内钉或钢板/螺钉治疗的年长患者,实验室检查可能是合理的。基于证据的围手术期实验室检查建议有可能提高质量和价值,并将儿科骨科创伤中的伤害降至最低。

证据水平

III级——回顾性比较研究(治疗性)。

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