Clinic of Nuclear Medicine and PET/CT Center, Imaging Institute of Southern Switzerland, Bellinzona, Switzerland.
Health Technology Assessment Unit, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Endocrine. 2020 Jan;67(1):9-19. doi: 10.1007/s12020-019-02131-4. Epub 2019 Nov 16.
In the last few years, the role and use of medical technologies in (neuro)endocrine oncology has greatly evolved allowing not only important diagnostic information but also prognostic stratification in different clinical situations. The terms "prognostic" and "predictive" are commonly used to describe the relationships between biomarkers and patients' clinical outcomes but have quite different meaning. The present work discusses the prognostic and predictive value of nuclear medicine imaging. It critically reviews the clinical significance and potential impact of molecular examinations on follow-up and therapeutic strategies in patients with neuroendocrine neoplasms, thyroid tumors, and adrenal malignancies.
在过去的几年中，医学技术在（神经）内分泌肿瘤学中的作用和用途发生了巨大的变化，不仅提供了重要的诊断信息，而且在不同的临床情况下也进行了预后分层。“预后”和“预测”这两个术语通常用于描述生物标志物与患者临床结局之间的关系，但它们的含义却截然不同。本文讨论了核医学成像的预后和预测价值。它批判性地回顾了分子检查在神经内分泌肿瘤、甲状腺肿瘤和肾上腺恶性肿瘤患者的随访和治疗策略中的临床意义和潜在影响。
