Stockley R A
Q J Med. 1979 Jul;48(191):419-28.
The clinical and radiological features of 23 patients with cor pulmonale due to chronic obstructive airways disease were reviewed. Twenty-two patients had evidence of pulmonary vascular disease and 52 per cent had secondary polycythaemia. Eighteen (78 per cent) had radiological evidence of emphysema. Thirteen of the patients (56.5 per cent) had alpha 1-antitrypsin phenotypes associated with serum deficiency and of these the largest single group was the MZ phenotype (34.8 per cent). No difference was found between the clinical features of patients with the MM phenotype or those associated with alpha 1-antitrypsin deficiency, although radiological emphysema was more common in the latter group (92 per cent compared to 60 per cent).
对23例慢性阻塞性气道疾病所致肺心病患者的临床和放射学特征进行了回顾。22例患者有肺血管疾病的证据，52%有继发性红细胞增多症。18例（78%）有肺气肿的放射学证据。13例患者（56.5%）具有与血清缺乏相关的α1 -抗胰蛋白酶表型，其中最大的单一组是MZ表型（34.8%）。MM表型患者与α1 -抗胰蛋白酶缺乏相关患者的临床特征未发现差异，尽管放射学肺气肿在后一组中更常见（分别为92%和60%）。
