Wan Qi, Tang Jing, Han Yu, Ye Hongquan
Department of Ophthalmology, The People's Hospital of Leshan, Leshan City, 614000, People's Republic of China.
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510064, China.
Int Ophthalmol. 2020 Jan;40(1):43-49. doi: 10.1007/s10792-019-01201-w. Epub 2019 Nov 17.
To report a novel technique to treat superficial limbal dermoid by using the corneal intrastromal lenticules obtained from SMILE and to evaluate the initial clinical outcomes of lenticule patch graft for treatment of limbal dermoid.
In this single-center case series, lenticules were obtained from patients undergoing SMILE for the correction of myopia and the lenticule patch graft was performed in three patients with limbal dermoid. Patients were postoperatively followed at first, second weeks and first, third months after surgery. The main measured outcome parameters were included the best-corrected visual acuity, transparency of graft, tectonic integrity and restoration of optical transparency.
All surgeries were successful, and all patients recovered well. Obviously, improving tendency in visual acuity and astigmatism was seen at the final follow-up in all eyes. No statistically significant difference has found in the thickness of the cornea between the surgical field and the corresponding normal field. Globe integrity was achieved in all cases, and no immune rejection or perforation was detected until the last follow-up visit in all eyes treated.
Lenticule keratoplasty may be a safe, feasible and inexpensive surgical option for the treatment of corneal dermoid. It retains globe integrity and decreases the risk of complications such as postoperative limbal ectasia and visible corneal scarring and should be widely promoted in the areas with shortage of donor corneas.
报告一种使用小切口基质透镜切除术(SMILE)获取的角膜基质透镜治疗浅层角膜缘皮样瘤的新技术,并评估透镜补片移植治疗角膜缘皮样瘤的初步临床效果。
在这个单中心病例系列中,从接受SMILE矫正近视的患者身上获取透镜,并对3例角膜缘皮样瘤患者进行透镜补片移植。术后在第1周、第2周以及术后第1个月、第3个月对患者进行随访。主要测量的结果参数包括最佳矫正视力、移植片透明度、结构完整性和光学透明度的恢复情况。
所有手术均成功,所有患者恢复良好。显然,所有术眼在最终随访时视力和散光均有改善趋势。手术区域与相应正常区域的角膜厚度之间未发现统计学上的显著差异。所有病例均保持眼球完整性,直至最后一次随访,所有治疗的术眼均未检测到免疫排斥或穿孔。
透镜角膜移植术可能是治疗角膜皮样瘤的一种安全、可行且廉价的手术选择。它能保持眼球完整性,并降低诸如术后角膜缘扩张和明显角膜瘢痕等并发症的风险,在供体角膜短缺的地区应广泛推广。