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儿童鼻内神经胶质异位症:两例报告及文献综述

Nasal glial heterotopia in children: Two case reports and literature review.

作者信息

Yan Yang-Yan, Zhou Zhi-Ying, Bi Jing, Fu Yong

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Hangzhou, China.

Department of Otorhinolaryngology, Head and Neck Surgery, Children's Hospital, Zhejiang University School of Medicine, Binsheng Road 3333, Hangzhou, China.

出版信息

Int J Pediatr Otorhinolaryngol. 2020 Feb;129:109728. doi: 10.1016/j.ijporl.2019.109728. Epub 2019 Oct 15.

Abstract

Nasal glial heterotopia is a rare developmental anomaly. We present two cases of nasal glial heterotopia. The presenting symptoms, imaging findings, treatment, histological appearance, and follow-up are described in detail. We additionally reviewed all pediatric cases of nasal glial heterotopia published between 1980 and 2018 in the PubMed and Baidu Scholar databases. We identified 60 pediatric patients (36 [60%] boys). The main symptoms were nasal congestion and open-mouth breathing. Treatment was successful in all patients, and the recurrence rate was low (3/60, 5%). Nasal glial heterotopia requires multidisciplinary management but has a good prognosis.

摘要

鼻内神经胶质异位是一种罕见的发育异常。我们报告两例鼻内神经胶质异位病例。详细描述了其临床表现、影像学表现、治疗方法、组织学表现及随访情况。我们还检索了1980年至2018年间发表在PubMed和百度学术数据库中的所有儿童鼻内神经胶质异位病例。我们共纳入60例儿童患者(36例[60%]为男性)。主要症状为鼻塞和张口呼吸。所有患者治疗均成功,复发率低(3/60,5%)。鼻内神经胶质异位需要多学科管理,但预后良好。

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