妇科恶性肿瘤。
Gynecologic Malignancies.
机构信息
Department of Radiation Oncology, University of Utah, 1950 Circle of Hope, Salt Lake City, UT 84112, USA.
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Johns Hopkins Kimmel Cancer Center, The Weinberg Building, 401 North Broadway, Room 1454, Baltimore, MD 21287, USA. Electronic address: https://twitter.com/anvjhu.edu.
出版信息
Hematol Oncol Clin North Am. 2020 Feb;34(1):71-89. doi: 10.1016/j.hoc.2019.08.018.
Gynecologic malignancies are among the most prevalent cancers affecting women worldwide, but they are heterogeneous diseases with varying risk factors, management paradigms, and outcomes. Gynecologic cancers mediated by human papillomavirus (HPV) are preventable and curable with early detection and treatment. Dramatic reductions in cervical cancer incidence and mortality have been achieved through cancer screening and HPV vaccination. Radiotherapy plays a central role in the management of gynecologic malignancies. For some cancers, radiotherapy alone can be curative. More often, radiotherapy is used in conjunction with surgery and systemic therapy to improve locoregional control and extend overall survival. This chapter reviews recent advances in radiotherapeutic management of gynecologic malignancies.
妇科恶性肿瘤是全球女性最常见的癌症之一，但它们是异质性疾病，具有不同的危险因素、管理模式和结局。人乳头瘤病毒（HPV）介导的妇科癌症是可以预防和治愈的，通过早期发现和治疗。通过癌症筛查和 HPV 疫苗接种，宫颈癌的发病率和死亡率已经显著降低。放射治疗在妇科恶性肿瘤的治疗中起着核心作用。对于某些癌症，单独放疗即可治愈。更常见的是，放疗与手术和全身治疗联合使用，以提高局部区域控制率并延长总生存期。本章回顾了妇科恶性肿瘤放射治疗管理的最新进展。
Zotero 插件