Margolis T, Irvine A R, Hoyt W F, Hyman R
Department of Ophthalmology, University of California, San Francisco.
Ophthalmology. 1988 Jul;95(7):937-40. doi: 10.1016/s0161-6420(88)33072-1.
Acute retinal necrosis (ARN) syndrome is a diffuse uveitis characterized by a peripheral necrotizing retinitis and retinal vasculitis. The authors document and discuss a case of ARN syndrome that initially presented with remarkable changes in the peripapillary retinal nerve fiber layer that they have termed arcuate neuroretinitis. These changes consisted of a well-defined arcuate band of retinitis paralleling the course of a parafoveal nerve fiber bundle. Evaluation of serial serum antibody titers suggests HSV-2 as a possible causative agent in this unique presentation of ARN syndrome.
