Jokelainen M, Wikström J, Palo J
Acta Neurol Scand. 1979;60(5):283-8. doi: 10.1111/j.1600-0404.1979.tb02983.x.
After World War II the southeastern part of Finland was ceded to the Soviet Union and its entire population evacuated to other areas of the country. The prevalences of amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) were studied among the evacuees and compared to the corresponding data among the nonevacuated population. The prevalence of ALS among the war evacuees was two times higher than among the nonevacuated population (18.0 and 8.8 per 100,000, respectively). The prevalence of MS among the evacuees was only half of that found among the nonevacuated population, 38.3 and 73.0 per 100,000, respectively. The findings for ALS indicate that birthplace may have an effect on the later development of the disease and that there may have existed some environmental factor(s) which have made the evacuees more liable to contract the disease later in their lives. The low figure of MS for evacuees supports our previous results of an uneven geographic distribution of MS in Finland with the high-risk areas in the western and southwestern parts of the country. No accumulation of MS was found among the evacuees living in the high-risk areas.
第二次世界大战后，芬兰东南部被割让给苏联，其全部人口被疏散到该国其他地区。对疏散人员中的肌萎缩侧索硬化症（ALS）和多发性硬化症（MS）患病率进行了研究，并与未疏散人群的相应数据进行了比较。战争疏散人员中ALS的患病率比未疏散人群高出两倍（分别为每10万人18.0例和8.8例）。疏散人员中MS的患病率仅为未疏散人群的一半，分别为每10万人38.3例和73.0例。ALS的研究结果表明，出生地可能对该疾病的后期发展有影响，并且可能存在一些环境因素，使疏散人员在晚年更容易患上这种疾病。疏散人员中MS的低患病率支持了我们之前关于芬兰MS地理分布不均的结果，该国西部和西南部为高风险地区。在居住在高风险地区的疏散人员中未发现MS的聚集情况。
