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芬兰的肌萎缩侧索硬化症。I:一项流行病学研究。

Amyotrophic lateral sclerosis in Finland. I: An epidemiologic study.

作者信息

Jokelainen M

出版信息

Acta Neurol Scand. 1977 Sep;56(3):185-93. doi: 10.1111/j.1600-0404.1977.tb01424.x.

DOI:10.1111/j.1600-0404.1977.tb01424.x
PMID:906793
Abstract

The prevalence of ALS and its distribution in Finland was investigated on the basis of prevalence numbers by counties. On the prevalence day, 1 January 1973, 168 ALS patients were found alive. They were collected from hospital records and the registers of the National Pension Institute. The prevalence was 3.56 cases per 100,000 populations, 4.25/100,000 for men and 1.92/100,000 for women, which gave a male to female prevalence ration 1.5 to 1. The distribution of the disease was uneven in the country being more frequent in the southeastern counties. The disease was contracted earlier (at 51.9 years of age) and its course was slower (3.7 years up to the prevalence day) in the prevalence material than in cases derived from the mortality statistics (58.0 years at the onset and duration of 2.6 years, respectively). This is explained by the dropping out of some of the younger and/or more benign cases from the mortality statistics. This seems to be true also in other countries.

摘要

基于各县的患病率数据,对芬兰肌萎缩侧索硬化症(ALS)的患病率及其分布情况进行了调查。在患病率统计日,即1973年1月1日,发现有168例ALS患者存活。这些患者是从医院记录和国家养老金机构的登记册中收集的。患病率为每10万人中有3.56例,男性为4.25/10万,女性为1.92/10万,男女患病率之比为1.5比1。该疾病在该国的分布并不均匀,在东南部各县更为常见。与来自死亡率统计数据的病例相比(发病年龄分别为58.0岁,病程为2.6年),患病率统计资料中的疾病发病更早(51.9岁),病程更慢(至患病率统计日为3.7年)。这是因为一些较年轻和/或病情较轻的病例从死亡率统计数据中遗漏了。在其他国家似乎也是如此。

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