Mirdamadi Ahmad, Mirmohammadsadeghi Mohsen, Banazade Dardashty Amir, Arabi Zahra
Department of Heart, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, Iran.
Department of Cardiac Surgery, Isfahan University of Medical Science, Isfahan, Iran.
J Res Med Sci. 2019 Oct 25;24:93. doi: 10.4103/jrms.JRMS_1024_17. eCollection 2019.
The significant association between epicardial adipose tissue and cardiovascular risk factors as well as outcome of ischemic heart diseases has been recently proposed. We determined the association between epicardial adipose tissue thickness and in-hospital as well as 3-month outcome after coronary artery bypass grafting surgery (CABG).
This cross-sectional study was performed on 78 consecutive patients who underwent CABG in our heart center. Associations between epicardial adipose tissue thickness and in-hospital as well as 3-month outcome after CABG were measured by logistic regression and value of epicardial fat thickness evaluated by receiver operating characteristic (ROC) curve analysis.
Patients in-intensive care unit (ICU) suffered a variety of events, which many of them were insignificant, but 23 events (29.4%) of 78 were considered as important. The most frequent complication occurred in ICU was atrial fibrillation (9%). The frequency of 3-month complications was 6.4%, including 3.8% rehospitalization, 1.3% reoperation, and 1.3% cardiac death. Ninety-day mortality rate was 1.3%. Mean epicardial adipose tissue thickness was significantly higher in those with in-ICU complications than those without complication (7.64 ± 2.80 mm vs. 6.16 ± 2.29 mm, = 0.015); however, the difference for 90-day complications was statistically nonsignificant. According to ROC curve analysis, measuring epicardial adipose tissue thickness could moderately predict in-ICU complication (area under the curve = 0.65 8, 95% confidence interval: 0.536-0.779, = 0.017). The best cut-off point of this adipose tissue thickness for predicting in-ICU complication was 6.5 mm with sensitivity of 65.9% and specificity of 58.8%.
Epicardial adipose tissue thickness is a useful predicting parameter for in-ICU complications after CABG.
最近有人提出心外膜脂肪组织与心血管危险因素以及缺血性心脏病的预后之间存在显著关联。我们确定了冠状动脉旁路移植术（CABG）后心外膜脂肪组织厚度与住院期间以及3个月预后之间的关联。
本横断面研究对我们心脏中心连续78例行CABG的患者进行。通过逻辑回归测量心外膜脂肪组织厚度与CABG后住院期间以及3个月预后之间的关联，并通过受试者工作特征（ROC）曲线分析评估心外膜脂肪厚度值。
重症监护病房（ICU）的患者发生了各种事件，其中许多无足轻重，但78例中有23例（29.4%）被认为是重要事件。ICU中最常见的并发症是心房颤动（9%）。3个月并发症的发生率为6.4%，包括3.8%的再次住院、1.3%的再次手术和1.3%的心源性死亡。90天死亡率为1.3%。ICU中有并发症的患者的心外膜脂肪组织平均厚度显著高于无并发症的患者（7.64±2.80毫米对6.16±2.29毫米，P=0.015）；然而，90天并发症的差异在统计学上无显著意义。根据ROC曲线分析，测量心外膜脂肪组织厚度可适度预测ICU中的并发症（曲线下面积=0.658，95%置信区间：0.536 - 0.779，P=0.017）。该脂肪组织厚度预测ICU中并发症的最佳切点为6.5毫米，敏感性为65.9%，特异性为58.8%。
心外膜脂肪组织厚度是CABG后ICU中并发症的有用预测参数。
